Thermodynamic and kinetic investigation of monoketo-aldehyde-peroxyhemiacetal (MKA), a stereolabile degradation product of dihydroartemisinin

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Bibliographische Detailangaben
Zeitschriftentitel:	RSC Adv.
Personen und Körperschaften:	Kotoni, D., Piras, M., Cabri, W., Giorgi, F., Mazzanti, A., Pierini, M., Quaglia, M., Villani, C., Gasparrini, F.
In:	RSC Adv., 4, 2014, 62, S. 32847-32857
Format:	E-Article
Sprache:	Englisch
veröffentlicht:	Royal Society of Chemistry (RSC)
Schlagwörter:	General Chemical Engineering General Chemistry

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Zusammenfassung:	<p>The<bold>β</bold>⇆<bold>α</bold>epimerization process of<bold>MKA</bold>has been studied under a thermodynamic and kinetic point of view in several solvents. LSER analyses and molecular modeling calculations allowed an effective rationalization of the findings.</p>
Umfang:	32847-32857
ISSN:	2046-2069
DOI:	10.1039/c4ra00879k