author_facet Garcia, Tiago S.
Engelholm, Jean-Luc
Vouche, Michaël
Hirakata, Vânia N.
Leitão, Cristiane B.
Garcia, Tiago S.
Engelholm, Jean-Luc
Vouche, Michaël
Hirakata, Vânia N.
Leitão, Cristiane B.
author Garcia, Tiago S.
Engelholm, Jean-Luc
Vouche, Michaël
Hirakata, Vânia N.
Leitão, Cristiane B.
spellingShingle Garcia, Tiago S.
Engelholm, Jean-Luc
Vouche, Michaël
Hirakata, Vânia N.
Leitão, Cristiane B.
Scientific Reports
Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
Multidisciplinary
author_sort garcia, tiago s.
spelling Garcia, Tiago S. Engelholm, Jean-Luc Vouche, Michaël Hirakata, Vânia N. Leitão, Cristiane B. 2045-2322 Springer Science and Business Media LLC Multidisciplinary http://dx.doi.org/10.1038/s41598-019-42519-w <jats:title>Abstract</jats:title><jats:p>The aim of this study was to measure intra- and interobserver agreement among radiologists in the assessment of pancreatic perfusion by computed tomography (CT). Thirty-nine perfusion CT scans were analyzed. The following parameters were measured by three readers: blood flow (BF), blood volume (BV), mean transit time (MTT) and time to peak (TTP). Statistical analysis was performed using the Bland-Altman method, linear mixed model analysis, and intraclass correlation coefficient (ICC). There was no significant intraobserver variability for the readers regarding BF, BV or TTP. There were session effects for BF in the pancreatic body and MTT in the pancreatic tail and whole pancreas. There were reader effects for BV in the pancreatic head, pancreatic body and whole pancreas. There were no effects for the interaction between session and reader for any perfusion parameter. ICCs showed substantial agreement for the interobserver measurements and moderate to substantial agreement for the intraobserver measurements, with the exception of MTT. In conclusion, satisfactory reproducibility of measurements was observed for TTP in all pancreatic regions, for BF in the head and BV in the tail, and these parameters seem to ensure a reasonable estimation of pancreatic perfusion.</jats:p> Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography Scientific Reports
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title Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_unstemmed Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_full Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_fullStr Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_full_unstemmed Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_short Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_sort intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
topic Multidisciplinary
url http://dx.doi.org/10.1038/s41598-019-42519-w
publishDate 2019
physical
description <jats:title>Abstract</jats:title><jats:p>The aim of this study was to measure intra- and interobserver agreement among radiologists in the assessment of pancreatic perfusion by computed tomography (CT). Thirty-nine perfusion CT scans were analyzed. The following parameters were measured by three readers: blood flow (BF), blood volume (BV), mean transit time (MTT) and time to peak (TTP). Statistical analysis was performed using the Bland-Altman method, linear mixed model analysis, and intraclass correlation coefficient (ICC). There was no significant intraobserver variability for the readers regarding BF, BV or TTP. There were session effects for BF in the pancreatic body and MTT in the pancreatic tail and whole pancreas. There were reader effects for BV in the pancreatic head, pancreatic body and whole pancreas. There were no effects for the interaction between session and reader for any perfusion parameter. ICCs showed substantial agreement for the interobserver measurements and moderate to substantial agreement for the intraobserver measurements, with the exception of MTT. In conclusion, satisfactory reproducibility of measurements was observed for TTP in all pancreatic regions, for BF in the head and BV in the tail, and these parameters seem to ensure a reasonable estimation of pancreatic perfusion.</jats:p>
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author Garcia, Tiago S., Engelholm, Jean-Luc, Vouche, Michaël, Hirakata, Vânia N., Leitão, Cristiane B.
author_facet Garcia, Tiago S., Engelholm, Jean-Luc, Vouche, Michaël, Hirakata, Vânia N., Leitão, Cristiane B., Garcia, Tiago S., Engelholm, Jean-Luc, Vouche, Michaël, Hirakata, Vânia N., Leitão, Cristiane B.
author_sort garcia, tiago s.
container_issue 1
container_start_page 0
container_title Scientific Reports
container_volume 9
description <jats:title>Abstract</jats:title><jats:p>The aim of this study was to measure intra- and interobserver agreement among radiologists in the assessment of pancreatic perfusion by computed tomography (CT). Thirty-nine perfusion CT scans were analyzed. The following parameters were measured by three readers: blood flow (BF), blood volume (BV), mean transit time (MTT) and time to peak (TTP). Statistical analysis was performed using the Bland-Altman method, linear mixed model analysis, and intraclass correlation coefficient (ICC). There was no significant intraobserver variability for the readers regarding BF, BV or TTP. There were session effects for BF in the pancreatic body and MTT in the pancreatic tail and whole pancreas. There were reader effects for BV in the pancreatic head, pancreatic body and whole pancreas. There were no effects for the interaction between session and reader for any perfusion parameter. ICCs showed substantial agreement for the interobserver measurements and moderate to substantial agreement for the intraobserver measurements, with the exception of MTT. In conclusion, satisfactory reproducibility of measurements was observed for TTP in all pancreatic regions, for BF in the head and BV in the tail, and these parameters seem to ensure a reasonable estimation of pancreatic perfusion.</jats:p>
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spelling Garcia, Tiago S. Engelholm, Jean-Luc Vouche, Michaël Hirakata, Vânia N. Leitão, Cristiane B. 2045-2322 Springer Science and Business Media LLC Multidisciplinary http://dx.doi.org/10.1038/s41598-019-42519-w <jats:title>Abstract</jats:title><jats:p>The aim of this study was to measure intra- and interobserver agreement among radiologists in the assessment of pancreatic perfusion by computed tomography (CT). Thirty-nine perfusion CT scans were analyzed. The following parameters were measured by three readers: blood flow (BF), blood volume (BV), mean transit time (MTT) and time to peak (TTP). Statistical analysis was performed using the Bland-Altman method, linear mixed model analysis, and intraclass correlation coefficient (ICC). There was no significant intraobserver variability for the readers regarding BF, BV or TTP. There were session effects for BF in the pancreatic body and MTT in the pancreatic tail and whole pancreas. There were reader effects for BV in the pancreatic head, pancreatic body and whole pancreas. There were no effects for the interaction between session and reader for any perfusion parameter. ICCs showed substantial agreement for the interobserver measurements and moderate to substantial agreement for the intraobserver measurements, with the exception of MTT. In conclusion, satisfactory reproducibility of measurements was observed for TTP in all pancreatic regions, for BF in the head and BV in the tail, and these parameters seem to ensure a reasonable estimation of pancreatic perfusion.</jats:p> Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography Scientific Reports
spellingShingle Garcia, Tiago S., Engelholm, Jean-Luc, Vouche, Michaël, Hirakata, Vânia N., Leitão, Cristiane B., Scientific Reports, Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography, Multidisciplinary
title Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_full Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_fullStr Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_full_unstemmed Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_short Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_sort intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
title_unstemmed Intra- and interobserver reproducibility of pancreatic perfusion by computed tomography
topic Multidisciplinary
url http://dx.doi.org/10.1038/s41598-019-42519-w