Eintrag weiter verarbeiten
Solitary peripapillary hemangioblastoma : A histopathological case report: A histopathological case report
Gespeichert in:
| Zeitschriftentitel: | Acta Ophthalmologica Scandinavica |
|---|---|
| Personen und Körperschaften: | , |
| In: | Acta Ophthalmologica Scandinavica, 79, 2001, 1, S. 83-87 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Joussen, Antonia M. Kirchhof, Bernd Joussen, Antonia M. Kirchhof, Bernd |
|---|---|
| author |
Joussen, Antonia M. Kirchhof, Bernd |
| spellingShingle |
Joussen, Antonia M. Kirchhof, Bernd Acta Ophthalmologica Scandinavica Solitary peripapillary hemangioblastoma : A histopathological case report Ophthalmology |
| author_sort |
joussen, antonia m. |
| spelling |
Joussen, Antonia M. Kirchhof, Bernd 1395-3907 1600-0420 Wiley Ophthalmology http://dx.doi.org/10.1034/j.1600-0420.2001.079001083.x <jats:p><jats:bold>ABSTRACT.</jats:bold><jats:bold> Purpose:</jats:bold> Hemangioblastomas are highly vascularized tumors of not well‐defined histological origin. They are the most frequent manifestation of the von‐Hippel‐Lindau (VHL) disease, but also occur as sporadic non‐hereditary tumors. Much has been learned in the recent past about the genetic background, however, the cellular origin of the tumor is still not resolved.</jats:p><jats:p><jats:bold>Methods:</jats:bold> We report a rare case of sporadic peripapillary hemangioblastoma in a 58‐year‐old patient.</jats:p><jats:p><jats:bold>Results:</jats:bold> Histological examination demonstrated a highly vascularized tumor with intercapillary stromal cells. The tumor did not invade the adjacent tissues. Surrounding retinal areas showed cystic and gliotic changes. Immunohistochemistry was unable to prove neuroglial origin of the stromal cells.</jats:p><jats:p><jats:bold>Conclusion:</jats:bold> Histological findings show similarities to the findings in cerebral hemangioblastomas. The tumor location in this case together with the known response of glial cells to VHL, might indicate their involvement in the pathogenesis of hemangioblastoma.</jats:p> A histopathological case report Solitary peripapillary hemangioblastoma : A histopathological case report Acta Ophthalmologica Scandinavica |
| doi_str_mv |
10.1034/j.1600-0420.2001.079001083.x |
| facet_avail |
Online Free |
| finc_class_facet |
Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAzNC9qLjE2MDAtMDQyMC4yMDAxLjA3OTAwMTA4My54 |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAzNC9qLjE2MDAtMDQyMC4yMDAxLjA3OTAwMTA4My54 |
| institution |
DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 DE-L229 DE-D275 DE-Bn3 |
| imprint |
Wiley, 2001 |
| imprint_str_mv |
Wiley, 2001 |
| issn |
1395-3907 1600-0420 |
| issn_str_mv |
1395-3907 1600-0420 |
| language |
English |
| mega_collection |
Wiley (CrossRef) |
| match_str |
joussen2001solitaryperipapillaryhemangioblastomaahistopathologicalcasereportahistopathologicalcasereport |
| publishDateSort |
2001 |
| publisher |
Wiley |
| recordtype |
ai |
| record_format |
ai |
| series |
Acta Ophthalmologica Scandinavica |
| source_id |
49 |
| title_sub |
A histopathological case report |
| title |
Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_unstemmed |
Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_full |
Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_fullStr |
Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_full_unstemmed |
Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_short |
Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_sort |
solitary peripapillary hemangioblastoma : a histopathological case report |
| topic |
Ophthalmology |
| url |
http://dx.doi.org/10.1034/j.1600-0420.2001.079001083.x |
| publishDate |
2001 |
| physical |
83-87 |
| description |
<jats:p><jats:bold>ABSTRACT.</jats:bold><jats:bold> Purpose:</jats:bold> Hemangioblastomas are highly vascularized tumors of not well‐defined histological origin. They are the most frequent manifestation of the von‐Hippel‐Lindau (VHL) disease, but also occur as sporadic non‐hereditary tumors. Much has been learned in the recent past about the genetic background, however, the cellular origin of the tumor is still not resolved.</jats:p><jats:p><jats:bold>Methods:</jats:bold> We report a rare case of sporadic peripapillary hemangioblastoma in a 58‐year‐old patient.</jats:p><jats:p><jats:bold>Results:</jats:bold> Histological examination demonstrated a highly vascularized tumor with intercapillary stromal cells. The tumor did not invade the adjacent tissues. Surrounding retinal areas showed cystic and gliotic changes. Immunohistochemistry was unable to prove neuroglial origin of the stromal cells.</jats:p><jats:p><jats:bold>Conclusion:</jats:bold> Histological findings show similarities to the findings in cerebral hemangioblastomas. The tumor location in this case together with the known response of glial cells to VHL, might indicate their involvement in the pathogenesis of hemangioblastoma.</jats:p> |
| container_issue |
1 |
| container_start_page |
83 |
| container_title |
Acta Ophthalmologica Scandinavica |
| container_volume |
79 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792336181147467782 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T14:56:22.106Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Solitary+peripapillary+hemangioblastoma+%3A+A+histopathological+case+report&rft.date=2001-02-01&genre=article&issn=1600-0420&volume=79&issue=1&spage=83&epage=87&pages=83-87&jtitle=Acta+Ophthalmologica+Scandinavica&atitle=Solitary+peripapillary+hemangioblastoma+%3A+A+histopathological+case+report&aulast=Kirchhof&aufirst=Bernd&rft_id=info%3Adoi%2F10.1034%2Fj.1600-0420.2001.079001083.x&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792336181147467782 |
| author | Joussen, Antonia M., Kirchhof, Bernd |
| author_facet | Joussen, Antonia M., Kirchhof, Bernd, Joussen, Antonia M., Kirchhof, Bernd |
| author_sort | joussen, antonia m. |
| container_issue | 1 |
| container_start_page | 83 |
| container_title | Acta Ophthalmologica Scandinavica |
| container_volume | 79 |
| description | <jats:p><jats:bold>ABSTRACT.</jats:bold><jats:bold> Purpose:</jats:bold> Hemangioblastomas are highly vascularized tumors of not well‐defined histological origin. They are the most frequent manifestation of the von‐Hippel‐Lindau (VHL) disease, but also occur as sporadic non‐hereditary tumors. Much has been learned in the recent past about the genetic background, however, the cellular origin of the tumor is still not resolved.</jats:p><jats:p><jats:bold>Methods:</jats:bold> We report a rare case of sporadic peripapillary hemangioblastoma in a 58‐year‐old patient.</jats:p><jats:p><jats:bold>Results:</jats:bold> Histological examination demonstrated a highly vascularized tumor with intercapillary stromal cells. The tumor did not invade the adjacent tissues. Surrounding retinal areas showed cystic and gliotic changes. Immunohistochemistry was unable to prove neuroglial origin of the stromal cells.</jats:p><jats:p><jats:bold>Conclusion:</jats:bold> Histological findings show similarities to the findings in cerebral hemangioblastomas. The tumor location in this case together with the known response of glial cells to VHL, might indicate their involvement in the pathogenesis of hemangioblastoma.</jats:p> |
| doi_str_mv | 10.1034/j.1600-0420.2001.079001083.x |
| facet_avail | Online, Free |
| finc_class_facet | Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAzNC9qLjE2MDAtMDQyMC4yMDAxLjA3OTAwMTA4My54 |
| imprint | Wiley, 2001 |
| imprint_str_mv | Wiley, 2001 |
| institution | DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3 |
| issn | 1395-3907, 1600-0420 |
| issn_str_mv | 1395-3907, 1600-0420 |
| language | English |
| last_indexed | 2024-03-01T14:56:22.106Z |
| match_str | joussen2001solitaryperipapillaryhemangioblastomaahistopathologicalcasereportahistopathologicalcasereport |
| mega_collection | Wiley (CrossRef) |
| physical | 83-87 |
| publishDate | 2001 |
| publishDateSort | 2001 |
| publisher | Wiley |
| record_format | ai |
| recordtype | ai |
| series | Acta Ophthalmologica Scandinavica |
| source_id | 49 |
| spelling | Joussen, Antonia M. Kirchhof, Bernd 1395-3907 1600-0420 Wiley Ophthalmology http://dx.doi.org/10.1034/j.1600-0420.2001.079001083.x <jats:p><jats:bold>ABSTRACT.</jats:bold><jats:bold> Purpose:</jats:bold> Hemangioblastomas are highly vascularized tumors of not well‐defined histological origin. They are the most frequent manifestation of the von‐Hippel‐Lindau (VHL) disease, but also occur as sporadic non‐hereditary tumors. Much has been learned in the recent past about the genetic background, however, the cellular origin of the tumor is still not resolved.</jats:p><jats:p><jats:bold>Methods:</jats:bold> We report a rare case of sporadic peripapillary hemangioblastoma in a 58‐year‐old patient.</jats:p><jats:p><jats:bold>Results:</jats:bold> Histological examination demonstrated a highly vascularized tumor with intercapillary stromal cells. The tumor did not invade the adjacent tissues. Surrounding retinal areas showed cystic and gliotic changes. Immunohistochemistry was unable to prove neuroglial origin of the stromal cells.</jats:p><jats:p><jats:bold>Conclusion:</jats:bold> Histological findings show similarities to the findings in cerebral hemangioblastomas. The tumor location in this case together with the known response of glial cells to VHL, might indicate their involvement in the pathogenesis of hemangioblastoma.</jats:p> A histopathological case report Solitary peripapillary hemangioblastoma : A histopathological case report Acta Ophthalmologica Scandinavica |
| spellingShingle | Joussen, Antonia M., Kirchhof, Bernd, Acta Ophthalmologica Scandinavica, Solitary peripapillary hemangioblastoma : A histopathological case report, Ophthalmology |
| title | Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_full | Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_fullStr | Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_full_unstemmed | Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_short | Solitary peripapillary hemangioblastoma : A histopathological case report |
| title_sort | solitary peripapillary hemangioblastoma : a histopathological case report |
| title_sub | A histopathological case report |
| title_unstemmed | Solitary peripapillary hemangioblastoma : A histopathological case report |
| topic | Ophthalmology |
| url | http://dx.doi.org/10.1034/j.1600-0420.2001.079001083.x |