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Dietary calcium intake and rate of bone loss in men
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| Zeitschriftentitel: | British Journal of Nutrition |
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| Personen und Körperschaften: | , , , |
| In: | British Journal of Nutrition, 117, 2017, 10, S. 1432-1438 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Cambridge University Press (CUP)
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| Schlagwörter: |
| Zusammenfassung: | <jats:title>Abstract</jats:title><jats:p>A high Ca intake has been recommended for osteoporosis prevention; however, little research has examined the relationship between dietary Ca and bone health in men. We examined associations between dietary Ca intake, bone mineral density (BMD) and change in BMD at the total body, hip and spine over 2 years in a cohort of men (mean age 57 years, BMI 26 kg/m<jats:sup>2</jats:sup>) from a trial. Data from the total cohort (<jats:italic>n</jats:italic>323) were used in the analysis of Ca intake and BMD at baseline, and data from the placebo group (<jats:italic>n</jats:italic>99) were used in the longitudinal analysis of Ca intake and change in BMD. Parathyroid hormone (PTH) and the markers of bone turnover serum total alkaline phosphatase activity, serum C-telopeptide and serum procollagen type-1 N-terminal propeptide were measured in a subset of participants at baseline (<jats:italic>n</jats:italic>150), and associations with dietary Ca at baseline were examined. Mean Ca intake was 870 mg/d. Baseline BMD was not related to dietary Ca intake at any site, before or after adjustment for covariables. Similarly, bone loss over 2 years was not related to Ca intake at any site, before or after adjustment. Dietary Ca intake was inversely correlated with PTH at baseline (<jats:italic>r</jats:italic>−0·19,<jats:italic>P</jats:italic>=0·02), but was not associated with the markers of bone turnover. BMD and rates of bone loss were unrelated to Ca intake in these men. This suggests that strategies to increase Ca intake are unlikely to impact on the prevalence of and morbidity from male osteoporosis.</jats:p> |
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| Umfang: | 1432-1438 |
| ISSN: |
1475-2662
0007-1145 |
| DOI: | 10.1017/s0007114517001301 |