Eintrag weiter verarbeiten
Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis
Gespeichert in:
| Zeitschriftentitel: | Journal of Clinical Laboratory Analysis |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , |
| In: | Journal of Clinical Laboratory Analysis, 29, 2015, 4, S. 294-298 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Gökmen, Ferhat Akbal, Ayla Reşorlu, Hatice Gökmen, Esra Güven, Mustafa Aras, Adem Bozkurt Erbağ, Gökhan Kömürcü, Erkam Akbal, Erdem Coşar, Murat Gökmen, Ferhat Akbal, Ayla Reşorlu, Hatice Gökmen, Esra Güven, Mustafa Aras, Adem Bozkurt Erbağ, Gökhan Kömürcü, Erkam Akbal, Erdem Coşar, Murat |
|---|---|
| author |
Gökmen, Ferhat Akbal, Ayla Reşorlu, Hatice Gökmen, Esra Güven, Mustafa Aras, Adem Bozkurt Erbağ, Gökhan Kömürcü, Erkam Akbal, Erdem Coşar, Murat |
| spellingShingle |
Gökmen, Ferhat Akbal, Ayla Reşorlu, Hatice Gökmen, Esra Güven, Mustafa Aras, Adem Bozkurt Erbağ, Gökhan Kömürcü, Erkam Akbal, Erdem Coşar, Murat Journal of Clinical Laboratory Analysis Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis Microbiology (medical) Biochemistry (medical) Medical Laboratory Technology Clinical Biochemistry Public Health, Environmental and Occupational Health Hematology Immunology and Allergy |
| author_sort |
gökmen, ferhat |
| spelling |
Gökmen, Ferhat Akbal, Ayla Reşorlu, Hatice Gökmen, Esra Güven, Mustafa Aras, Adem Bozkurt Erbağ, Gökhan Kömürcü, Erkam Akbal, Erdem Coşar, Murat 0887-8013 1098-2825 Wiley Microbiology (medical) Biochemistry (medical) Medical Laboratory Technology Clinical Biochemistry Public Health, Environmental and Occupational Health Hematology Immunology and Allergy http://dx.doi.org/10.1002/jcla.21768 <jats:sec><jats:title>Background</jats:title><jats:p>In recent years, white blood cells (WBCs) and their subtypes have been studied in relation to inflammation. The aim of our study was to assess the relationship between neutrophil–lymphocyte ratio (NLR) and ankylosing spondylitis (AS).</jats:p></jats:sec><jats:sec><jats:title>Materials and methods</jats:title><jats:p>We enrolled a total of 177 patients, 96 AS and 81 healthy controls. Complete blood count, WBC, neutrophil and lymphocyte levels were measured, and the NLR was calculated. In the assessment of AS, we used the erythrocyte sedimentation rate, C‐reactive protein (CRP), the Bath Ankylosing Spondylitis Disease Activity Index, and the Bath Ankylosing Spondylitis Functional Index.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>In the present study, 96 AS and 81 healthy individuals were enrolled. The mean age was 43.8 ± 12.9 and 46.5 ± 11.2 years, respectively. Mean disease duration of AS patients was 6.9 ± 5.6 years (median = 5, min–max = 1–25). The patients with AS had a higher NLR than the control individuals (mean NLR, 2.24 ± 1.23 and 1.73 ± 0.70, respectively, <jats:italic>P</jats:italic> < 0.001). A statistically significant positive correlation was observed between NLR and CRP (<jats:italic>r</jats:italic> = 0.322, <jats:italic>P</jats:italic> = 0.01). The patients receiving antitumor necrosis factor α therapy had a lower NLR than the patients receiving nonsteroidal anti‐inflammatory drug therapy (mean NLR, 1.71 ± 0.62 and 2.41 ± 1.33, respectively, <jats:italic>P</jats:italic> = 0.02).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>NLR may be seen as a useful marker for demonstrating inflammation together with acute phase reactants such as CRP and in evaluating the effectiveness of anti‐TNF‐α therapy.</jats:p></jats:sec> Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis Journal of Clinical Laboratory Analysis |
| doi_str_mv |
10.1002/jcla.21768 |
| facet_avail |
Online Free |
| finc_class_facet |
Biologie Medizin Technik Chemie und Pharmazie |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9qY2xhLjIxNzY4 |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9qY2xhLjIxNzY4 |
| institution |
DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 DE-L229 |
| imprint |
Wiley, 2015 |
| imprint_str_mv |
Wiley, 2015 |
| issn |
0887-8013 1098-2825 |
| issn_str_mv |
0887-8013 1098-2825 |
| language |
English |
| mega_collection |
Wiley (CrossRef) |
| match_str |
gokmen2015neutrophillymphocyteratioconnectedtotreatmentoptionsandinflammationmarkersofankylosingspondylitis |
| publishDateSort |
2015 |
| publisher |
Wiley |
| recordtype |
ai |
| record_format |
ai |
| series |
Journal of Clinical Laboratory Analysis |
| source_id |
49 |
| title |
Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_unstemmed |
Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_full |
Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_fullStr |
Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_full_unstemmed |
Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_short |
Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_sort |
neutrophil–lymphocyte ratio connected to treatment options and inflammation markers of ankylosing spondylitis |
| topic |
Microbiology (medical) Biochemistry (medical) Medical Laboratory Technology Clinical Biochemistry Public Health, Environmental and Occupational Health Hematology Immunology and Allergy |
| url |
http://dx.doi.org/10.1002/jcla.21768 |
| publishDate |
2015 |
| physical |
294-298 |
| description |
<jats:sec><jats:title>Background</jats:title><jats:p>In recent years, white blood cells (WBCs) and their subtypes have been studied in relation to inflammation. The aim of our study was to assess the relationship between neutrophil–lymphocyte ratio (NLR) and ankylosing spondylitis (AS).</jats:p></jats:sec><jats:sec><jats:title>Materials and methods</jats:title><jats:p>We enrolled a total of 177 patients, 96 AS and 81 healthy controls. Complete blood count, WBC, neutrophil and lymphocyte levels were measured, and the NLR was calculated. In the assessment of AS, we used the erythrocyte sedimentation rate, C‐reactive protein (CRP), the Bath Ankylosing Spondylitis Disease Activity Index, and the Bath Ankylosing Spondylitis Functional Index.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>In the present study, 96 AS and 81 healthy individuals were enrolled. The mean age was 43.8 ± 12.9 and 46.5 ± 11.2 years, respectively. Mean disease duration of AS patients was 6.9 ± 5.6 years (median = 5, min–max = 1–25). The patients with AS had a higher NLR than the control individuals (mean NLR, 2.24 ± 1.23 and 1.73 ± 0.70, respectively, <jats:italic>P</jats:italic> < 0.001). A statistically significant positive correlation was observed between NLR and CRP (<jats:italic>r</jats:italic> = 0.322, <jats:italic>P</jats:italic> = 0.01). The patients receiving antitumor necrosis factor α therapy had a lower NLR than the patients receiving nonsteroidal anti‐inflammatory drug therapy (mean NLR, 1.71 ± 0.62 and 2.41 ± 1.33, respectively, <jats:italic>P</jats:italic> = 0.02).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>NLR may be seen as a useful marker for demonstrating inflammation together with acute phase reactants such as CRP and in evaluating the effectiveness of anti‐TNF‐α therapy.</jats:p></jats:sec> |
| container_issue |
4 |
| container_start_page |
294 |
| container_title |
Journal of Clinical Laboratory Analysis |
| container_volume |
29 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792347290036338690 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T17:52:56.21Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Neutrophil%E2%80%93Lymphocyte+Ratio+Connected+to+Treatment+Options+and+Inflammation+Markers+of+Ankylosing+Spondylitis&rft.date=2015-07-01&genre=article&issn=1098-2825&volume=29&issue=4&spage=294&epage=298&pages=294-298&jtitle=Journal+of+Clinical+Laboratory+Analysis&atitle=Neutrophil%E2%80%93Lymphocyte+Ratio+Connected+to+Treatment+Options+and+Inflammation+Markers+of+Ankylosing+Spondylitis&aulast=Co%C5%9Far&aufirst=Murat&rft_id=info%3Adoi%2F10.1002%2Fjcla.21768&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792347290036338690 |
| author | Gökmen, Ferhat, Akbal, Ayla, Reşorlu, Hatice, Gökmen, Esra, Güven, Mustafa, Aras, Adem Bozkurt, Erbağ, Gökhan, Kömürcü, Erkam, Akbal, Erdem, Coşar, Murat |
| author_facet | Gökmen, Ferhat, Akbal, Ayla, Reşorlu, Hatice, Gökmen, Esra, Güven, Mustafa, Aras, Adem Bozkurt, Erbağ, Gökhan, Kömürcü, Erkam, Akbal, Erdem, Coşar, Murat, Gökmen, Ferhat, Akbal, Ayla, Reşorlu, Hatice, Gökmen, Esra, Güven, Mustafa, Aras, Adem Bozkurt, Erbağ, Gökhan, Kömürcü, Erkam, Akbal, Erdem, Coşar, Murat |
| author_sort | gökmen, ferhat |
| container_issue | 4 |
| container_start_page | 294 |
| container_title | Journal of Clinical Laboratory Analysis |
| container_volume | 29 |
| description | <jats:sec><jats:title>Background</jats:title><jats:p>In recent years, white blood cells (WBCs) and their subtypes have been studied in relation to inflammation. The aim of our study was to assess the relationship between neutrophil–lymphocyte ratio (NLR) and ankylosing spondylitis (AS).</jats:p></jats:sec><jats:sec><jats:title>Materials and methods</jats:title><jats:p>We enrolled a total of 177 patients, 96 AS and 81 healthy controls. Complete blood count, WBC, neutrophil and lymphocyte levels were measured, and the NLR was calculated. In the assessment of AS, we used the erythrocyte sedimentation rate, C‐reactive protein (CRP), the Bath Ankylosing Spondylitis Disease Activity Index, and the Bath Ankylosing Spondylitis Functional Index.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>In the present study, 96 AS and 81 healthy individuals were enrolled. The mean age was 43.8 ± 12.9 and 46.5 ± 11.2 years, respectively. Mean disease duration of AS patients was 6.9 ± 5.6 years (median = 5, min–max = 1–25). The patients with AS had a higher NLR than the control individuals (mean NLR, 2.24 ± 1.23 and 1.73 ± 0.70, respectively, <jats:italic>P</jats:italic> < 0.001). A statistically significant positive correlation was observed between NLR and CRP (<jats:italic>r</jats:italic> = 0.322, <jats:italic>P</jats:italic> = 0.01). The patients receiving antitumor necrosis factor α therapy had a lower NLR than the patients receiving nonsteroidal anti‐inflammatory drug therapy (mean NLR, 1.71 ± 0.62 and 2.41 ± 1.33, respectively, <jats:italic>P</jats:italic> = 0.02).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>NLR may be seen as a useful marker for demonstrating inflammation together with acute phase reactants such as CRP and in evaluating the effectiveness of anti‐TNF‐α therapy.</jats:p></jats:sec> |
| doi_str_mv | 10.1002/jcla.21768 |
| facet_avail | Online, Free |
| finc_class_facet | Biologie, Medizin, Technik, Chemie und Pharmazie |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9qY2xhLjIxNzY4 |
| imprint | Wiley, 2015 |
| imprint_str_mv | Wiley, 2015 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
| issn | 0887-8013, 1098-2825 |
| issn_str_mv | 0887-8013, 1098-2825 |
| language | English |
| last_indexed | 2024-03-01T17:52:56.21Z |
| match_str | gokmen2015neutrophillymphocyteratioconnectedtotreatmentoptionsandinflammationmarkersofankylosingspondylitis |
| mega_collection | Wiley (CrossRef) |
| physical | 294-298 |
| publishDate | 2015 |
| publishDateSort | 2015 |
| publisher | Wiley |
| record_format | ai |
| recordtype | ai |
| series | Journal of Clinical Laboratory Analysis |
| source_id | 49 |
| spelling | Gökmen, Ferhat Akbal, Ayla Reşorlu, Hatice Gökmen, Esra Güven, Mustafa Aras, Adem Bozkurt Erbağ, Gökhan Kömürcü, Erkam Akbal, Erdem Coşar, Murat 0887-8013 1098-2825 Wiley Microbiology (medical) Biochemistry (medical) Medical Laboratory Technology Clinical Biochemistry Public Health, Environmental and Occupational Health Hematology Immunology and Allergy http://dx.doi.org/10.1002/jcla.21768 <jats:sec><jats:title>Background</jats:title><jats:p>In recent years, white blood cells (WBCs) and their subtypes have been studied in relation to inflammation. The aim of our study was to assess the relationship between neutrophil–lymphocyte ratio (NLR) and ankylosing spondylitis (AS).</jats:p></jats:sec><jats:sec><jats:title>Materials and methods</jats:title><jats:p>We enrolled a total of 177 patients, 96 AS and 81 healthy controls. Complete blood count, WBC, neutrophil and lymphocyte levels were measured, and the NLR was calculated. In the assessment of AS, we used the erythrocyte sedimentation rate, C‐reactive protein (CRP), the Bath Ankylosing Spondylitis Disease Activity Index, and the Bath Ankylosing Spondylitis Functional Index.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>In the present study, 96 AS and 81 healthy individuals were enrolled. The mean age was 43.8 ± 12.9 and 46.5 ± 11.2 years, respectively. Mean disease duration of AS patients was 6.9 ± 5.6 years (median = 5, min–max = 1–25). The patients with AS had a higher NLR than the control individuals (mean NLR, 2.24 ± 1.23 and 1.73 ± 0.70, respectively, <jats:italic>P</jats:italic> < 0.001). A statistically significant positive correlation was observed between NLR and CRP (<jats:italic>r</jats:italic> = 0.322, <jats:italic>P</jats:italic> = 0.01). The patients receiving antitumor necrosis factor α therapy had a lower NLR than the patients receiving nonsteroidal anti‐inflammatory drug therapy (mean NLR, 1.71 ± 0.62 and 2.41 ± 1.33, respectively, <jats:italic>P</jats:italic> = 0.02).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>NLR may be seen as a useful marker for demonstrating inflammation together with acute phase reactants such as CRP and in evaluating the effectiveness of anti‐TNF‐α therapy.</jats:p></jats:sec> Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis Journal of Clinical Laboratory Analysis |
| spellingShingle | Gökmen, Ferhat, Akbal, Ayla, Reşorlu, Hatice, Gökmen, Esra, Güven, Mustafa, Aras, Adem Bozkurt, Erbağ, Gökhan, Kömürcü, Erkam, Akbal, Erdem, Coşar, Murat, Journal of Clinical Laboratory Analysis, Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis, Microbiology (medical), Biochemistry (medical), Medical Laboratory Technology, Clinical Biochemistry, Public Health, Environmental and Occupational Health, Hematology, Immunology and Allergy |
| title | Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_full | Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_fullStr | Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_full_unstemmed | Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_short | Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| title_sort | neutrophil–lymphocyte ratio connected to treatment options and inflammation markers of ankylosing spondylitis |
| title_unstemmed | Neutrophil–Lymphocyte Ratio Connected to Treatment Options and Inflammation Markers of Ankylosing Spondylitis |
| topic | Microbiology (medical), Biochemistry (medical), Medical Laboratory Technology, Clinical Biochemistry, Public Health, Environmental and Occupational Health, Hematology, Immunology and Allergy |
| url | http://dx.doi.org/10.1002/jcla.21768 |