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Multilocus sequence typing (MLST) analysis of Vibrio cholerae O1 El Tor isolates from Mozambique that harbour the classical CTX prophage

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Bibliographische Detailangaben
Zeitschriftentitel: Journal of Medical Microbiology
Personen und Körperschaften: Lee, Je Hee, Han, Kyung Ho, Choi, Seon Young, Lucas, Marcelino E. S., Mondlane, C., Ansaruzzaman, M., Nair, G. Balakrish, Sack, David A., von Seidlein, Lorenz, Clemens, John D., Song, Manki, Chun, Jongsik, Kim, Dong Wook
In: Journal of Medical Microbiology, 55, 2006, 2, S. 165-170
Format: E-Article
Sprache: Englisch
veröffentlicht:
Microbiology Society
Schlagwörter:
Microbiology (medical)
General Medicine
Microbiology
Details
Zusammenfassung: <jats:p> <jats:italic>Vibrio cholerae</jats:italic> O1 isolates belonging to the Ogawa serotype, El Tor biotype, harbouring the classical CTX prophage were first isolated in Mozambique in 2004. Multilocus sequence typing (MLST) analysis using nine genetic loci showed that the Mozambique isolates have the same sequence type (ST) as O1 El Tor N16961, a representative of the current seventh cholera pandemic. Analysis of the CTX prophage in the Mozambique isolates indicated that there is one type of <jats:italic>rstR</jats:italic> in these isolates: the classical CTX prophage. It was also found that the <jats:italic>ctxB</jats:italic>-<jats:italic>rstR</jats:italic>-<jats:italic>rstA</jats:italic>-<jats:italic>rstB</jats:italic>-<jats:italic>phs</jats:italic>-<jats:italic>cep</jats:italic> fragment was PCR-amplified from these isolates, which indicates the presence of a tandem repeat of the classical CTX prophage in the genome of the Mozambique isolates. The possible origin of these isolates and the presence of the tandem repeat of the classical prophage in them implicate the presence of the classical CTX phage.</jats:p>
Umfang: 165-170
ISSN: 0022-2615
1473-5644
DOI: 10.1099/jmm.0.46287-0