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Expression quantitative trait loci: present and future
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Zeitschriftentitel: | Philosophical Transactions of the Royal Society B: Biological Sciences |
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Personen und Körperschaften: | , |
In: | Philosophical Transactions of the Royal Society B: Biological Sciences, 368, 2013, 1620, S. 20120362 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
The Royal Society
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Schlagwörter: |
author_facet |
Nica, Alexandra C. Dermitzakis, Emmanouil T. Nica, Alexandra C. Dermitzakis, Emmanouil T. |
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author |
Nica, Alexandra C. Dermitzakis, Emmanouil T. |
spellingShingle |
Nica, Alexandra C. Dermitzakis, Emmanouil T. Philosophical Transactions of the Royal Society B: Biological Sciences Expression quantitative trait loci: present and future General Agricultural and Biological Sciences General Biochemistry, Genetics and Molecular Biology |
author_sort |
nica, alexandra c. |
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Nica, Alexandra C. Dermitzakis, Emmanouil T. 0962-8436 1471-2970 The Royal Society General Agricultural and Biological Sciences General Biochemistry, Genetics and Molecular Biology http://dx.doi.org/10.1098/rstb.2012.0362 <jats:p>The last few years have seen the development of large efforts for the analysis of genome function, especially in the context of genome variation. One of the most prominent directions has been the extensive set of studies on expression quantitative trait loci (eQTLs), namely, the discovery of genetic variants that explain variation in gene expression levels. Such studies have offered promise not just for the characterization of functional sequence variation but also for the understanding of basic processes of gene regulation and interpretation of genome-wide association studies. In this review, we discuss some of the key directions of eQTL research and its implications.</jats:p> Expression quantitative trait loci: present and future Philosophical Transactions of the Royal Society B: Biological Sciences |
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title |
Expression quantitative trait loci: present and future |
title_unstemmed |
Expression quantitative trait loci: present and future |
title_full |
Expression quantitative trait loci: present and future |
title_fullStr |
Expression quantitative trait loci: present and future |
title_full_unstemmed |
Expression quantitative trait loci: present and future |
title_short |
Expression quantitative trait loci: present and future |
title_sort |
expression quantitative trait loci: present and future |
topic |
General Agricultural and Biological Sciences General Biochemistry, Genetics and Molecular Biology |
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http://dx.doi.org/10.1098/rstb.2012.0362 |
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2013 |
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20120362 |
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<jats:p>The last few years have seen the development of large efforts for the analysis of genome function, especially in the context of genome variation. One of the most prominent directions has been the extensive set of studies on expression quantitative trait loci (eQTLs), namely, the discovery of genetic variants that explain variation in gene expression levels. Such studies have offered promise not just for the characterization of functional sequence variation but also for the understanding of basic processes of gene regulation and interpretation of genome-wide association studies. In this review, we discuss some of the key directions of eQTL research and its implications.</jats:p> |
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author | Nica, Alexandra C., Dermitzakis, Emmanouil T. |
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description | <jats:p>The last few years have seen the development of large efforts for the analysis of genome function, especially in the context of genome variation. One of the most prominent directions has been the extensive set of studies on expression quantitative trait loci (eQTLs), namely, the discovery of genetic variants that explain variation in gene expression levels. Such studies have offered promise not just for the characterization of functional sequence variation but also for the understanding of basic processes of gene regulation and interpretation of genome-wide association studies. In this review, we discuss some of the key directions of eQTL research and its implications.</jats:p> |
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spelling | Nica, Alexandra C. Dermitzakis, Emmanouil T. 0962-8436 1471-2970 The Royal Society General Agricultural and Biological Sciences General Biochemistry, Genetics and Molecular Biology http://dx.doi.org/10.1098/rstb.2012.0362 <jats:p>The last few years have seen the development of large efforts for the analysis of genome function, especially in the context of genome variation. One of the most prominent directions has been the extensive set of studies on expression quantitative trait loci (eQTLs), namely, the discovery of genetic variants that explain variation in gene expression levels. Such studies have offered promise not just for the characterization of functional sequence variation but also for the understanding of basic processes of gene regulation and interpretation of genome-wide association studies. In this review, we discuss some of the key directions of eQTL research and its implications.</jats:p> Expression quantitative trait loci: present and future Philosophical Transactions of the Royal Society B: Biological Sciences |
spellingShingle | Nica, Alexandra C., Dermitzakis, Emmanouil T., Philosophical Transactions of the Royal Society B: Biological Sciences, Expression quantitative trait loci: present and future, General Agricultural and Biological Sciences, General Biochemistry, Genetics and Molecular Biology |
title | Expression quantitative trait loci: present and future |
title_full | Expression quantitative trait loci: present and future |
title_fullStr | Expression quantitative trait loci: present and future |
title_full_unstemmed | Expression quantitative trait loci: present and future |
title_short | Expression quantitative trait loci: present and future |
title_sort | expression quantitative trait loci: present and future |
title_unstemmed | Expression quantitative trait loci: present and future |
topic | General Agricultural and Biological Sciences, General Biochemistry, Genetics and Molecular Biology |
url | http://dx.doi.org/10.1098/rstb.2012.0362 |