Eintrag weiter verarbeiten
Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas
Gespeichert in:
| Zeitschriftentitel: | Molecular Biology and Evolution |
|---|---|
| Personen und Körperschaften: | , , , , , , |
| In: | Molecular Biology and Evolution, 37, 2020, 6, S. 1577-1592 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Oxford University Press (OUP)
|
| Schlagwörter: |
| author_facet |
Wang, XiaoYun Liang, Dan Jin, Wei Tang, MingKun Shalayiwu Liu, ShaoYing Zhang, Peng Wang, XiaoYun Liang, Dan Jin, Wei Tang, MingKun Shalayiwu Liu, ShaoYing Zhang, Peng |
|---|---|
| author |
Wang, XiaoYun Liang, Dan Jin, Wei Tang, MingKun Shalayiwu Liu, ShaoYing Zhang, Peng |
| spellingShingle |
Wang, XiaoYun Liang, Dan Jin, Wei Tang, MingKun Shalayiwu Liu, ShaoYing Zhang, Peng Molecular Biology and Evolution Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas Genetics Molecular Biology Ecology, Evolution, Behavior and Systematics |
| author_sort |
wang, xiaoyun |
| spelling |
Wang, XiaoYun Liang, Dan Jin, Wei Tang, MingKun Shalayiwu Liu, ShaoYing Zhang, Peng 0737-4038 1537-1719 Oxford University Press (OUP) Genetics Molecular Biology Ecology, Evolution, Behavior and Systematics http://dx.doi.org/10.1093/molbev/msaa026 <jats:title>Abstract</jats:title><jats:p>Pikas are widely distributed in the Northern Hemisphere and are highly adapted to cold and alpine environments. They are one of the most complex and problematic groups in mammalian systematics, and the origin and evolutionary history of extant pikas remain controversial. In this study, we sequenced the whole coding sequences of 105 pika samples (29 named species and 1 putative new species) and obtained DNA data for more than 10,000 genes. Our phylogenomic analyses recognized four subgenera of extant pikas: Alienauroa, Conothoa, Ochotona, and Pika. The interrelationships between the four subgenera were strongly resolved as (Conothoa, (Alienauroa, (Ochotona, Pika))), with the mountain group Conothoa being the sister group of all other pikas. Our divergence time and phylogeographic analyses indicated that the last common ancestor of extant pikas first occurred on in the middle Miocene, ∼14 Ma. The emergence of opportunities related to the climate, food supply, and spreading paths in concert promoted the dispersal of pikas from the Qinghai-Tibetan Plateau (QTP) to other parts of Eurasia and North America. We found that the genes that were positively selected in the early evolution of pikas were most concentrated in functional categories related to cold tolerance. These results suggest that the QTP may have served as a training ground for cold tolerance in early pikas, which gives pikas a great advantage when the climate continued to cool after the middle Miocene. Our study highlights the importance of the QTP as a center of origin for many cold-adapted animals.</jats:p> Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas Molecular Biology and Evolution |
| doi_str_mv |
10.1093/molbev/msaa026 |
| facet_avail |
Online Free |
| finc_class_facet |
Biologie Geographie |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA5My9tb2xiZXYvbXNhYTAyNg |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA5My9tb2xiZXYvbXNhYTAyNg |
| institution |
DE-105 DE-14 DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 |
| imprint |
Oxford University Press (OUP), 2020 |
| imprint_str_mv |
Oxford University Press (OUP), 2020 |
| issn |
0737-4038 1537-1719 |
| issn_str_mv |
0737-4038 1537-1719 |
| language |
English |
| mega_collection |
Oxford University Press (OUP) (CrossRef) |
| match_str |
wang2020outoftibetgenomicperspectivesontheevolutionaryhistoryofextantpikas |
| publishDateSort |
2020 |
| publisher |
Oxford University Press (OUP) |
| recordtype |
ai |
| record_format |
ai |
| series |
Molecular Biology and Evolution |
| source_id |
49 |
| title |
Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_unstemmed |
Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_full |
Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_fullStr |
Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_full_unstemmed |
Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_short |
Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_sort |
out of tibet: genomic perspectives on the evolutionary history of extant pikas |
| topic |
Genetics Molecular Biology Ecology, Evolution, Behavior and Systematics |
| url |
http://dx.doi.org/10.1093/molbev/msaa026 |
| publishDate |
2020 |
| physical |
1577-1592 |
| description |
<jats:title>Abstract</jats:title><jats:p>Pikas are widely distributed in the Northern Hemisphere and are highly adapted to cold and alpine environments. They are one of the most complex and problematic groups in mammalian systematics, and the origin and evolutionary history of extant pikas remain controversial. In this study, we sequenced the whole coding sequences of 105 pika samples (29 named species and 1 putative new species) and obtained DNA data for more than 10,000 genes. Our phylogenomic analyses recognized four subgenera of extant pikas: Alienauroa, Conothoa, Ochotona, and Pika. The interrelationships between the four subgenera were strongly resolved as (Conothoa, (Alienauroa, (Ochotona, Pika))), with the mountain group Conothoa being the sister group of all other pikas. Our divergence time and phylogeographic analyses indicated that the last common ancestor of extant pikas first occurred on in the middle Miocene, ∼14 Ma. The emergence of opportunities related to the climate, food supply, and spreading paths in concert promoted the dispersal of pikas from the Qinghai-Tibetan Plateau (QTP) to other parts of Eurasia and North America. We found that the genes that were positively selected in the early evolution of pikas were most concentrated in functional categories related to cold tolerance. These results suggest that the QTP may have served as a training ground for cold tolerance in early pikas, which gives pikas a great advantage when the climate continued to cool after the middle Miocene. Our study highlights the importance of the QTP as a center of origin for many cold-adapted animals.</jats:p> |
| container_issue |
6 |
| container_start_page |
1577 |
| container_title |
Molecular Biology and Evolution |
| container_volume |
37 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792347574156394507 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T17:57:25.421Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Out+of+Tibet%3A+Genomic+Perspectives+on+the+Evolutionary+History+of+Extant+Pikas&rft.date=2020-06-01&genre=article&issn=1537-1719&volume=37&issue=6&spage=1577&epage=1592&pages=1577-1592&jtitle=Molecular+Biology+and+Evolution&atitle=Out+of+Tibet%3A+Genomic+Perspectives+on+the+Evolutionary+History+of+Extant+Pikas&aulast=Zhang&aufirst=Peng&rft_id=info%3Adoi%2F10.1093%2Fmolbev%2Fmsaa026&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792347574156394507 |
| author | Wang, XiaoYun, Liang, Dan, Jin, Wei, Tang, MingKun, Shalayiwu, Liu, ShaoYing, Zhang, Peng |
| author_facet | Wang, XiaoYun, Liang, Dan, Jin, Wei, Tang, MingKun, Shalayiwu, Liu, ShaoYing, Zhang, Peng, Wang, XiaoYun, Liang, Dan, Jin, Wei, Tang, MingKun, Shalayiwu, Liu, ShaoYing, Zhang, Peng |
| author_sort | wang, xiaoyun |
| container_issue | 6 |
| container_start_page | 1577 |
| container_title | Molecular Biology and Evolution |
| container_volume | 37 |
| description | <jats:title>Abstract</jats:title><jats:p>Pikas are widely distributed in the Northern Hemisphere and are highly adapted to cold and alpine environments. They are one of the most complex and problematic groups in mammalian systematics, and the origin and evolutionary history of extant pikas remain controversial. In this study, we sequenced the whole coding sequences of 105 pika samples (29 named species and 1 putative new species) and obtained DNA data for more than 10,000 genes. Our phylogenomic analyses recognized four subgenera of extant pikas: Alienauroa, Conothoa, Ochotona, and Pika. The interrelationships between the four subgenera were strongly resolved as (Conothoa, (Alienauroa, (Ochotona, Pika))), with the mountain group Conothoa being the sister group of all other pikas. Our divergence time and phylogeographic analyses indicated that the last common ancestor of extant pikas first occurred on in the middle Miocene, ∼14 Ma. The emergence of opportunities related to the climate, food supply, and spreading paths in concert promoted the dispersal of pikas from the Qinghai-Tibetan Plateau (QTP) to other parts of Eurasia and North America. We found that the genes that were positively selected in the early evolution of pikas were most concentrated in functional categories related to cold tolerance. These results suggest that the QTP may have served as a training ground for cold tolerance in early pikas, which gives pikas a great advantage when the climate continued to cool after the middle Miocene. Our study highlights the importance of the QTP as a center of origin for many cold-adapted animals.</jats:p> |
| doi_str_mv | 10.1093/molbev/msaa026 |
| facet_avail | Online, Free |
| finc_class_facet | Biologie, Geographie |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA5My9tb2xiZXYvbXNhYTAyNg |
| imprint | Oxford University Press (OUP), 2020 |
| imprint_str_mv | Oxford University Press (OUP), 2020 |
| institution | DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1 |
| issn | 0737-4038, 1537-1719 |
| issn_str_mv | 0737-4038, 1537-1719 |
| language | English |
| last_indexed | 2024-03-01T17:57:25.421Z |
| match_str | wang2020outoftibetgenomicperspectivesontheevolutionaryhistoryofextantpikas |
| mega_collection | Oxford University Press (OUP) (CrossRef) |
| physical | 1577-1592 |
| publishDate | 2020 |
| publishDateSort | 2020 |
| publisher | Oxford University Press (OUP) |
| record_format | ai |
| recordtype | ai |
| series | Molecular Biology and Evolution |
| source_id | 49 |
| spelling | Wang, XiaoYun Liang, Dan Jin, Wei Tang, MingKun Shalayiwu Liu, ShaoYing Zhang, Peng 0737-4038 1537-1719 Oxford University Press (OUP) Genetics Molecular Biology Ecology, Evolution, Behavior and Systematics http://dx.doi.org/10.1093/molbev/msaa026 <jats:title>Abstract</jats:title><jats:p>Pikas are widely distributed in the Northern Hemisphere and are highly adapted to cold and alpine environments. They are one of the most complex and problematic groups in mammalian systematics, and the origin and evolutionary history of extant pikas remain controversial. In this study, we sequenced the whole coding sequences of 105 pika samples (29 named species and 1 putative new species) and obtained DNA data for more than 10,000 genes. Our phylogenomic analyses recognized four subgenera of extant pikas: Alienauroa, Conothoa, Ochotona, and Pika. The interrelationships between the four subgenera were strongly resolved as (Conothoa, (Alienauroa, (Ochotona, Pika))), with the mountain group Conothoa being the sister group of all other pikas. Our divergence time and phylogeographic analyses indicated that the last common ancestor of extant pikas first occurred on in the middle Miocene, ∼14 Ma. The emergence of opportunities related to the climate, food supply, and spreading paths in concert promoted the dispersal of pikas from the Qinghai-Tibetan Plateau (QTP) to other parts of Eurasia and North America. We found that the genes that were positively selected in the early evolution of pikas were most concentrated in functional categories related to cold tolerance. These results suggest that the QTP may have served as a training ground for cold tolerance in early pikas, which gives pikas a great advantage when the climate continued to cool after the middle Miocene. Our study highlights the importance of the QTP as a center of origin for many cold-adapted animals.</jats:p> Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas Molecular Biology and Evolution |
| spellingShingle | Wang, XiaoYun, Liang, Dan, Jin, Wei, Tang, MingKun, Shalayiwu, Liu, ShaoYing, Zhang, Peng, Molecular Biology and Evolution, Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas, Genetics, Molecular Biology, Ecology, Evolution, Behavior and Systematics |
| title | Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_full | Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_fullStr | Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_full_unstemmed | Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_short | Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| title_sort | out of tibet: genomic perspectives on the evolutionary history of extant pikas |
| title_unstemmed | Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas |
| topic | Genetics, Molecular Biology, Ecology, Evolution, Behavior and Systematics |
| url | http://dx.doi.org/10.1093/molbev/msaa026 |