Eintrag weiter verarbeiten
Exon Array Analyzer: a web interface for Affymetrix exon array analysis
Gespeichert in:
| Zeitschriftentitel: | Bioinformatics |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Bioinformatics, 25, 2009, 24, S. 3323-3324 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Oxford University Press (OUP)
|
| Schlagwörter: |
| author_facet |
Gellert, Pascal Uchida, Shizuka Braun, Thomas Gellert, Pascal Uchida, Shizuka Braun, Thomas |
|---|---|
| author |
Gellert, Pascal Uchida, Shizuka Braun, Thomas |
| spellingShingle |
Gellert, Pascal Uchida, Shizuka Braun, Thomas Bioinformatics Exon Array Analyzer: a web interface for Affymetrix exon array analysis Computational Mathematics Computational Theory and Mathematics Computer Science Applications Molecular Biology Biochemistry Statistics and Probability |
| author_sort |
gellert, pascal |
| spelling |
Gellert, Pascal Uchida, Shizuka Braun, Thomas 1367-4811 1367-4803 Oxford University Press (OUP) Computational Mathematics Computational Theory and Mathematics Computer Science Applications Molecular Biology Biochemistry Statistics and Probability http://dx.doi.org/10.1093/bioinformatics/btp577 <jats:title>Abstract</jats:title> <jats:p>Summary: The Exon Array Analyzer (EAA) is a web server, which provides a user-friendly interface to identify alternative splicing events analyzed with Affymetrix Exon Arrays. The EAA implements the Splice Index algorithm to identify differential expressed exons. The use of various filters allows reduction of the number of false positive hits. Results are presented with detailed annotation information and graphics to identify splice events and to facilitate biological validations. To demonstrate the versatility of the EAA, we analyzed exon arrays of 11 different murine tissues using sample data provided by Affymetrix (http://www.affymetrix.com). Data from the heart were compared with other tissues to identify exons that undergo heart-specific alternatively splicing, resulting in the identification of 885 differentially expressed probe sets in 649 genes.</jats:p> <jats:p>Availability: The web interface is available at http://EAA.mpi-bn.mpg.de/. Detailed documentation is available on the EAA web site (http://EAA.mpi-bn.mpg.de/supp.php) including screen shots, example analyzes and step by step instructions.</jats:p> <jats:p>Contact: thomas.braun@mpi-bn.mpg.de</jats:p> <jats:p>Supplementary information: Supplementary data are available at Bioinformatics online.</jats:p> Exon Array Analyzer: a web interface for Affymetrix exon array analysis Bioinformatics |
| doi_str_mv |
10.1093/bioinformatics/btp577 |
| facet_avail |
Online Free |
| finc_class_facet |
Chemie und Pharmazie Mathematik Informatik Biologie |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA5My9iaW9pbmZvcm1hdGljcy9idHA1Nzc |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA5My9iaW9pbmZvcm1hdGljcy9idHA1Nzc |
| institution |
DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Zwi2 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 DE-L229 |
| imprint |
Oxford University Press (OUP), 2009 |
| imprint_str_mv |
Oxford University Press (OUP), 2009 |
| issn |
1367-4803 1367-4811 |
| issn_str_mv |
1367-4803 1367-4811 |
| language |
English |
| mega_collection |
Oxford University Press (OUP) (CrossRef) |
| match_str |
gellert2009exonarrayanalyzerawebinterfaceforaffymetrixexonarrayanalysis |
| publishDateSort |
2009 |
| publisher |
Oxford University Press (OUP) |
| recordtype |
ai |
| record_format |
ai |
| series |
Bioinformatics |
| source_id |
49 |
| title |
Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_unstemmed |
Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_full |
Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_fullStr |
Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_full_unstemmed |
Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_short |
Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_sort |
exon array analyzer: a web interface for affymetrix exon array analysis |
| topic |
Computational Mathematics Computational Theory and Mathematics Computer Science Applications Molecular Biology Biochemistry Statistics and Probability |
| url |
http://dx.doi.org/10.1093/bioinformatics/btp577 |
| publishDate |
2009 |
| physical |
3323-3324 |
| description |
<jats:title>Abstract</jats:title>
<jats:p>Summary: The Exon Array Analyzer (EAA) is a web server, which provides a user-friendly interface to identify alternative splicing events analyzed with Affymetrix Exon Arrays. The EAA implements the Splice Index algorithm to identify differential expressed exons. The use of various filters allows reduction of the number of false positive hits. Results are presented with detailed annotation information and graphics to identify splice events and to facilitate biological validations. To demonstrate the versatility of the EAA, we analyzed exon arrays of 11 different murine tissues using sample data provided by Affymetrix (http://www.affymetrix.com). Data from the heart were compared with other tissues to identify exons that undergo heart-specific alternatively splicing, resulting in the identification of 885 differentially expressed probe sets in 649 genes.</jats:p>
<jats:p>Availability: The web interface is available at http://EAA.mpi-bn.mpg.de/. Detailed documentation is available on the EAA web site (http://EAA.mpi-bn.mpg.de/supp.php) including screen shots, example analyzes and step by step instructions.</jats:p>
<jats:p>Contact: thomas.braun@mpi-bn.mpg.de</jats:p>
<jats:p>Supplementary information: Supplementary data are available at Bioinformatics online.</jats:p> |
| container_issue |
24 |
| container_start_page |
3323 |
| container_title |
Bioinformatics |
| container_volume |
25 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792336379065139202 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T14:59:15.851Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Exon+Array+Analyzer%3A+a+web+interface+for+Affymetrix+exon+array+analysis&rft.date=2009-12-15&genre=article&issn=1367-4803&volume=25&issue=24&spage=3323&epage=3324&pages=3323-3324&jtitle=Bioinformatics&atitle=Exon+Array+Analyzer%3A+a+web+interface+for+Affymetrix+exon+array+analysis&aulast=Braun&aufirst=Thomas&rft_id=info%3Adoi%2F10.1093%2Fbioinformatics%2Fbtp577&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792336379065139202 |
| author | Gellert, Pascal, Uchida, Shizuka, Braun, Thomas |
| author_facet | Gellert, Pascal, Uchida, Shizuka, Braun, Thomas, Gellert, Pascal, Uchida, Shizuka, Braun, Thomas |
| author_sort | gellert, pascal |
| container_issue | 24 |
| container_start_page | 3323 |
| container_title | Bioinformatics |
| container_volume | 25 |
| description | <jats:title>Abstract</jats:title> <jats:p>Summary: The Exon Array Analyzer (EAA) is a web server, which provides a user-friendly interface to identify alternative splicing events analyzed with Affymetrix Exon Arrays. The EAA implements the Splice Index algorithm to identify differential expressed exons. The use of various filters allows reduction of the number of false positive hits. Results are presented with detailed annotation information and graphics to identify splice events and to facilitate biological validations. To demonstrate the versatility of the EAA, we analyzed exon arrays of 11 different murine tissues using sample data provided by Affymetrix (http://www.affymetrix.com). Data from the heart were compared with other tissues to identify exons that undergo heart-specific alternatively splicing, resulting in the identification of 885 differentially expressed probe sets in 649 genes.</jats:p> <jats:p>Availability: The web interface is available at http://EAA.mpi-bn.mpg.de/. Detailed documentation is available on the EAA web site (http://EAA.mpi-bn.mpg.de/supp.php) including screen shots, example analyzes and step by step instructions.</jats:p> <jats:p>Contact: thomas.braun@mpi-bn.mpg.de</jats:p> <jats:p>Supplementary information: Supplementary data are available at Bioinformatics online.</jats:p> |
| doi_str_mv | 10.1093/bioinformatics/btp577 |
| facet_avail | Online, Free |
| finc_class_facet | Chemie und Pharmazie, Mathematik, Informatik, Biologie |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA5My9iaW9pbmZvcm1hdGljcy9idHA1Nzc |
| imprint | Oxford University Press (OUP), 2009 |
| imprint_str_mv | Oxford University Press (OUP), 2009 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Zwi2, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
| issn | 1367-4803, 1367-4811 |
| issn_str_mv | 1367-4803, 1367-4811 |
| language | English |
| last_indexed | 2024-03-01T14:59:15.851Z |
| match_str | gellert2009exonarrayanalyzerawebinterfaceforaffymetrixexonarrayanalysis |
| mega_collection | Oxford University Press (OUP) (CrossRef) |
| physical | 3323-3324 |
| publishDate | 2009 |
| publishDateSort | 2009 |
| publisher | Oxford University Press (OUP) |
| record_format | ai |
| recordtype | ai |
| series | Bioinformatics |
| source_id | 49 |
| spelling | Gellert, Pascal Uchida, Shizuka Braun, Thomas 1367-4811 1367-4803 Oxford University Press (OUP) Computational Mathematics Computational Theory and Mathematics Computer Science Applications Molecular Biology Biochemistry Statistics and Probability http://dx.doi.org/10.1093/bioinformatics/btp577 <jats:title>Abstract</jats:title> <jats:p>Summary: The Exon Array Analyzer (EAA) is a web server, which provides a user-friendly interface to identify alternative splicing events analyzed with Affymetrix Exon Arrays. The EAA implements the Splice Index algorithm to identify differential expressed exons. The use of various filters allows reduction of the number of false positive hits. Results are presented with detailed annotation information and graphics to identify splice events and to facilitate biological validations. To demonstrate the versatility of the EAA, we analyzed exon arrays of 11 different murine tissues using sample data provided by Affymetrix (http://www.affymetrix.com). Data from the heart were compared with other tissues to identify exons that undergo heart-specific alternatively splicing, resulting in the identification of 885 differentially expressed probe sets in 649 genes.</jats:p> <jats:p>Availability: The web interface is available at http://EAA.mpi-bn.mpg.de/. Detailed documentation is available on the EAA web site (http://EAA.mpi-bn.mpg.de/supp.php) including screen shots, example analyzes and step by step instructions.</jats:p> <jats:p>Contact: thomas.braun@mpi-bn.mpg.de</jats:p> <jats:p>Supplementary information: Supplementary data are available at Bioinformatics online.</jats:p> Exon Array Analyzer: a web interface for Affymetrix exon array analysis Bioinformatics |
| spellingShingle | Gellert, Pascal, Uchida, Shizuka, Braun, Thomas, Bioinformatics, Exon Array Analyzer: a web interface for Affymetrix exon array analysis, Computational Mathematics, Computational Theory and Mathematics, Computer Science Applications, Molecular Biology, Biochemistry, Statistics and Probability |
| title | Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_full | Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_fullStr | Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_full_unstemmed | Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_short | Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| title_sort | exon array analyzer: a web interface for affymetrix exon array analysis |
| title_unstemmed | Exon Array Analyzer: a web interface for Affymetrix exon array analysis |
| topic | Computational Mathematics, Computational Theory and Mathematics, Computer Science Applications, Molecular Biology, Biochemistry, Statistics and Probability |
| url | http://dx.doi.org/10.1093/bioinformatics/btp577 |