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Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling
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Zeitschriftentitel: | Molecular Biology of the Cell |
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Personen und Körperschaften: | , , , |
In: | Molecular Biology of the Cell, 32, 2021, 4, S. 348-361 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
American Society for Cell Biology (ASCB)
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Schlagwörter: |
author_facet |
Bunker, Eric N. Wheeler, Graycen E. Chapnick, Douglas A. Liu, Xuedong Bunker, Eric N. Wheeler, Graycen E. Chapnick, Douglas A. Liu, Xuedong |
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author |
Bunker, Eric N. Wheeler, Graycen E. Chapnick, Douglas A. Liu, Xuedong |
spellingShingle |
Bunker, Eric N. Wheeler, Graycen E. Chapnick, Douglas A. Liu, Xuedong Molecular Biology of the Cell Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling Cell Biology Molecular Biology |
author_sort |
bunker, eric n. |
spelling |
Bunker, Eric N. Wheeler, Graycen E. Chapnick, Douglas A. Liu, Xuedong 1059-1524 1939-4586 American Society for Cell Biology (ASCB) Cell Biology Molecular Biology http://dx.doi.org/10.1091/mbc.e19-08-0474 <jats:p> The loss of adherens junctions elevates autocrine TGF-α signaling in a TACE-dependent manner. Keratinocyte epithelial sheets depend on this signaling to propagate ERK activity for proliferation and motility signaling. </jats:p> Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling Molecular Biology of the Cell |
doi_str_mv |
10.1091/mbc.e19-08-0474 |
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Online Free |
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Biologie |
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American Society for Cell Biology (ASCB), 2021 |
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American Society for Cell Biology (ASCB), 2021 |
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1059-1524 1939-4586 |
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1059-1524 1939-4586 |
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2021 |
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American Society for Cell Biology (ASCB) |
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Molecular Biology of the Cell |
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49 |
title |
Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_unstemmed |
Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_full |
Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_fullStr |
Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_full_unstemmed |
Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_short |
Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_sort |
suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via tace-mediated tgf-α autocrine/paracrine signaling |
topic |
Cell Biology Molecular Biology |
url |
http://dx.doi.org/10.1091/mbc.e19-08-0474 |
publishDate |
2021 |
physical |
348-361 |
description |
<jats:p> The loss of adherens junctions elevates autocrine TGF-α signaling in a TACE-dependent manner. Keratinocyte epithelial sheets depend on this signaling to propagate ERK activity for proliferation and motility signaling. </jats:p> |
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Molecular Biology of the Cell |
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author | Bunker, Eric N., Wheeler, Graycen E., Chapnick, Douglas A., Liu, Xuedong |
author_facet | Bunker, Eric N., Wheeler, Graycen E., Chapnick, Douglas A., Liu, Xuedong, Bunker, Eric N., Wheeler, Graycen E., Chapnick, Douglas A., Liu, Xuedong |
author_sort | bunker, eric n. |
container_issue | 4 |
container_start_page | 348 |
container_title | Molecular Biology of the Cell |
container_volume | 32 |
description | <jats:p> The loss of adherens junctions elevates autocrine TGF-α signaling in a TACE-dependent manner. Keratinocyte epithelial sheets depend on this signaling to propagate ERK activity for proliferation and motility signaling. </jats:p> |
doi_str_mv | 10.1091/mbc.e19-08-0474 |
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imprint | American Society for Cell Biology (ASCB), 2021 |
imprint_str_mv | American Society for Cell Biology (ASCB), 2021 |
institution | DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Zwi2, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1 |
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issn_str_mv | 1059-1524, 1939-4586 |
language | English |
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mega_collection | American Society for Cell Biology (ASCB) (CrossRef) |
physical | 348-361 |
publishDate | 2021 |
publishDateSort | 2021 |
publisher | American Society for Cell Biology (ASCB) |
record_format | ai |
recordtype | ai |
series | Molecular Biology of the Cell |
source_id | 49 |
spelling | Bunker, Eric N. Wheeler, Graycen E. Chapnick, Douglas A. Liu, Xuedong 1059-1524 1939-4586 American Society for Cell Biology (ASCB) Cell Biology Molecular Biology http://dx.doi.org/10.1091/mbc.e19-08-0474 <jats:p> The loss of adherens junctions elevates autocrine TGF-α signaling in a TACE-dependent manner. Keratinocyte epithelial sheets depend on this signaling to propagate ERK activity for proliferation and motility signaling. </jats:p> Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling Molecular Biology of the Cell |
spellingShingle | Bunker, Eric N., Wheeler, Graycen E., Chapnick, Douglas A., Liu, Xuedong, Molecular Biology of the Cell, Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling, Cell Biology, Molecular Biology |
title | Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_full | Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_fullStr | Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_full_unstemmed | Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_short | Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
title_sort | suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via tace-mediated tgf-α autocrine/paracrine signaling |
title_unstemmed | Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling |
topic | Cell Biology, Molecular Biology |
url | http://dx.doi.org/10.1091/mbc.e19-08-0474 |