Eintrag weiter verarbeiten
Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato).
Gespeichert in:
| Zeitschriftentitel: | The Journal of general physiology |
|---|---|
| Personen und Körperschaften: | , , |
| In: | The Journal of general physiology, 68, 1976, 5, S. 503-518 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Rockefeller University Press
|
| Schlagwörter: |
| author_facet |
Weiss, J Goldman, Y Morad, M Weiss, J Goldman, Y Morad, M |
|---|---|
| author |
Weiss, J Goldman, Y Morad, M |
| spellingShingle |
Weiss, J Goldman, Y Morad, M The Journal of general physiology Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). Physiology |
| author_sort |
weiss, j |
| spelling |
Weiss, J Goldman, Y Morad, M 0022-1295 1540-7748 Rockefeller University Press Physiology http://dx.doi.org/10.1085/jgp.68.5.503 <jats:p>The tubular heart of the sea potato is composed of a single layer of myoepithelial cells interconnected near the extraluminal surface by specialized junctions. If these junctions are used as the border which separates the luminal from extraluminal membrane, the surface area ratio, luminal:extraluminal, is approximately 12:1. A single myofibril is located near the luminal surface in each cell. Current passed across the heart wall in the direction that depolarizes the luminal membrane and hyperpolarizes the extraluminal membrane immediately produces "all-or-none" action potentials and contractions. Current passed in the opposite direction fails to produce action potentials until after the break of the stimulus, suggesting anodal break excitation of the hyperpolarized luminal membrane. High potassium solutions depolarized the myoepithelium and produced contractions only when applied to the luminal surface of the heart. [Ca]0 increases and [Mg]0 decreases twitch tension only on the luminal surface of the heart. The transwall resistivity is low (50-100 omega/cm2) due to an extracellular shunt. Because of this shunt and the larger surface area of the luminal membrane, the extraluminal membrane is effectively clamped to the potential of the luminal membrane and is not capable of directly influencing excitation-contraction coupling. These findings suggest that only the luminal membrane of the sea potato myoepithelium is capable of generating an action potential and triggering contraction.</jats:p> Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). The Journal of general physiology |
| doi_str_mv |
10.1085/jgp.68.5.503 |
| facet_avail |
Online Free |
| finc_class_facet |
Biologie |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA4NS9qZ3AuNjguNS41MDM |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA4NS9qZ3AuNjguNS41MDM |
| institution |
DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 DE-L229 |
| imprint |
Rockefeller University Press, 1976 |
| imprint_str_mv |
Rockefeller University Press, 1976 |
| issn |
0022-1295 1540-7748 |
| issn_str_mv |
0022-1295 1540-7748 |
| language |
English |
| mega_collection |
Rockefeller University Press (CrossRef) |
| match_str |
weiss1976electromechanicalpropertiesofthesinglecelllayeredheartoftunicatebolteniaoviferaseapotato |
| publishDateSort |
1976 |
| publisher |
Rockefeller University Press |
| recordtype |
ai |
| record_format |
ai |
| series |
The Journal of general physiology |
| source_id |
49 |
| title |
Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_unstemmed |
Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_full |
Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_fullStr |
Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_full_unstemmed |
Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_short |
Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_sort |
electromechanical properties of the single cell-layered heart of tunicate boltenia ovifera (sea potato). |
| topic |
Physiology |
| url |
http://dx.doi.org/10.1085/jgp.68.5.503 |
| publishDate |
1976 |
| physical |
503-518 |
| description |
<jats:p>The tubular heart of the sea potato is composed of a single layer of myoepithelial cells interconnected near the extraluminal surface by specialized junctions. If these junctions are used as the border which separates the luminal from extraluminal membrane, the surface area ratio, luminal:extraluminal, is approximately 12:1. A single myofibril is located near the luminal surface in each cell. Current passed across the heart wall in the direction that depolarizes the luminal membrane and hyperpolarizes the extraluminal membrane immediately produces "all-or-none" action potentials and contractions. Current passed in the opposite direction fails to produce action potentials until after the break of the stimulus, suggesting anodal break excitation of the hyperpolarized luminal membrane. High potassium solutions depolarized the myoepithelium and produced contractions only when applied to the luminal surface of the heart. [Ca]0 increases and [Mg]0 decreases twitch tension only on the luminal surface of the heart. The transwall resistivity is low (50-100 omega/cm2) due to an extracellular shunt. Because of this shunt and the larger surface area of the luminal membrane, the extraluminal membrane is effectively clamped to the potential of the luminal membrane and is not capable of directly influencing excitation-contraction coupling. These findings suggest that only the luminal membrane of the sea potato myoepithelium is capable of generating an action potential and triggering contraction.</jats:p> |
| container_issue |
5 |
| container_start_page |
503 |
| container_title |
The Journal of general physiology |
| container_volume |
68 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792342794991304705 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T16:41:29.214Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Electromechanical+properties+of+the+single+cell-layered+heart+of+tunicate+Boltenia+ovifera+%28sea+potato%29.&rft.date=1976-11-01&genre=article&issn=1540-7748&volume=68&issue=5&spage=503&epage=518&pages=503-518&jtitle=The+Journal+of+general+physiology&atitle=Electromechanical+properties+of+the+single+cell-layered+heart+of+tunicate+Boltenia+ovifera+%28sea+potato%29.&aulast=Morad&aufirst=M&rft_id=info%3Adoi%2F10.1085%2Fjgp.68.5.503&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792342794991304705 |
| author | Weiss, J, Goldman, Y, Morad, M |
| author_facet | Weiss, J, Goldman, Y, Morad, M, Weiss, J, Goldman, Y, Morad, M |
| author_sort | weiss, j |
| container_issue | 5 |
| container_start_page | 503 |
| container_title | The Journal of general physiology |
| container_volume | 68 |
| description | <jats:p>The tubular heart of the sea potato is composed of a single layer of myoepithelial cells interconnected near the extraluminal surface by specialized junctions. If these junctions are used as the border which separates the luminal from extraluminal membrane, the surface area ratio, luminal:extraluminal, is approximately 12:1. A single myofibril is located near the luminal surface in each cell. Current passed across the heart wall in the direction that depolarizes the luminal membrane and hyperpolarizes the extraluminal membrane immediately produces "all-or-none" action potentials and contractions. Current passed in the opposite direction fails to produce action potentials until after the break of the stimulus, suggesting anodal break excitation of the hyperpolarized luminal membrane. High potassium solutions depolarized the myoepithelium and produced contractions only when applied to the luminal surface of the heart. [Ca]0 increases and [Mg]0 decreases twitch tension only on the luminal surface of the heart. The transwall resistivity is low (50-100 omega/cm2) due to an extracellular shunt. Because of this shunt and the larger surface area of the luminal membrane, the extraluminal membrane is effectively clamped to the potential of the luminal membrane and is not capable of directly influencing excitation-contraction coupling. These findings suggest that only the luminal membrane of the sea potato myoepithelium is capable of generating an action potential and triggering contraction.</jats:p> |
| doi_str_mv | 10.1085/jgp.68.5.503 |
| facet_avail | Online, Free |
| finc_class_facet | Biologie |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA4NS9qZ3AuNjguNS41MDM |
| imprint | Rockefeller University Press, 1976 |
| imprint_str_mv | Rockefeller University Press, 1976 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
| issn | 0022-1295, 1540-7748 |
| issn_str_mv | 0022-1295, 1540-7748 |
| language | English |
| last_indexed | 2024-03-01T16:41:29.214Z |
| match_str | weiss1976electromechanicalpropertiesofthesinglecelllayeredheartoftunicatebolteniaoviferaseapotato |
| mega_collection | Rockefeller University Press (CrossRef) |
| physical | 503-518 |
| publishDate | 1976 |
| publishDateSort | 1976 |
| publisher | Rockefeller University Press |
| record_format | ai |
| recordtype | ai |
| series | The Journal of general physiology |
| source_id | 49 |
| spelling | Weiss, J Goldman, Y Morad, M 0022-1295 1540-7748 Rockefeller University Press Physiology http://dx.doi.org/10.1085/jgp.68.5.503 <jats:p>The tubular heart of the sea potato is composed of a single layer of myoepithelial cells interconnected near the extraluminal surface by specialized junctions. If these junctions are used as the border which separates the luminal from extraluminal membrane, the surface area ratio, luminal:extraluminal, is approximately 12:1. A single myofibril is located near the luminal surface in each cell. Current passed across the heart wall in the direction that depolarizes the luminal membrane and hyperpolarizes the extraluminal membrane immediately produces "all-or-none" action potentials and contractions. Current passed in the opposite direction fails to produce action potentials until after the break of the stimulus, suggesting anodal break excitation of the hyperpolarized luminal membrane. High potassium solutions depolarized the myoepithelium and produced contractions only when applied to the luminal surface of the heart. [Ca]0 increases and [Mg]0 decreases twitch tension only on the luminal surface of the heart. The transwall resistivity is low (50-100 omega/cm2) due to an extracellular shunt. Because of this shunt and the larger surface area of the luminal membrane, the extraluminal membrane is effectively clamped to the potential of the luminal membrane and is not capable of directly influencing excitation-contraction coupling. These findings suggest that only the luminal membrane of the sea potato myoepithelium is capable of generating an action potential and triggering contraction.</jats:p> Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). The Journal of general physiology |
| spellingShingle | Weiss, J, Goldman, Y, Morad, M, The Journal of general physiology, Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato)., Physiology |
| title | Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_full | Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_fullStr | Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_full_unstemmed | Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_short | Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| title_sort | electromechanical properties of the single cell-layered heart of tunicate boltenia ovifera (sea potato). |
| title_unstemmed | Electromechanical properties of the single cell-layered heart of tunicate Boltenia ovifera (sea potato). |
| topic | Physiology |
| url | http://dx.doi.org/10.1085/jgp.68.5.503 |