author_facet Grigliatti, Thomas
Suzuki, David T.
Grigliatti, Thomas
Suzuki, David T.
author Grigliatti, Thomas
Suzuki, David T.
spellingShingle Grigliatti, Thomas
Suzuki, David T.
Proceedings of the National Academy of Sciences
Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
Multidisciplinary
author_sort grigliatti, thomas
spelling Grigliatti, Thomas Suzuki, David T. 0027-8424 1091-6490 Proceedings of the National Academy of Sciences Multidisciplinary http://dx.doi.org/10.1073/pnas.68.6.1307 <jats:p> There exists in <jats:italic>Drosophila</jats:italic> a class of mutations called “homeotic” that cause changes in determination of the imaginal discs. The homeotic mutant, <jats:italic> ss <jats:sup>a40a</jats:sup> </jats:italic> , was found to have a temperature-sensitive transformation of the arista segment of the antennal complex to a tarsus of the leg. In a selected stock penetrance was complete, so that at 29°C normal aristae were produced, whereas at 17°C complete tarsi developed in all flies. “Temperature-shift” studies revealed a temperature-sensitive period in the third larval instar. The temperature-initiated action of <jats:italic> ss <jats:sup>a40a</jats:sup> </jats:italic> does not appear to result from a simple wave or gradient of determination passing through the disc. Shifts up during the temperature-sensitive period yielded leg tissue proximally, which increased distally with progressively later shifts. Shifts down yielded leg tissue at the aristal base, which retreated with later shifts. </jats:p> Temperature-Sensitive Mutations in <i>Drosophila melanogaster</i> , VIII. The Homeotic Mutant, <i> ss <sup>a40a</sup> </i> Proceedings of the National Academy of Sciences
doi_str_mv 10.1073/pnas.68.6.1307
facet_avail Online
Free
format ElectronicArticle
fullrecord blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA3My9wbmFzLjY4LjYuMTMwNw
id ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA3My9wbmFzLjY4LjYuMTMwNw
institution DE-Zi4
DE-Gla1
DE-15
DE-Pl11
DE-Rs1
DE-14
DE-105
DE-Ch1
DE-L229
DE-D275
DE-Bn3
DE-Brt1
DE-Zwi2
DE-D161
imprint Proceedings of the National Academy of Sciences, 1971
imprint_str_mv Proceedings of the National Academy of Sciences, 1971
issn 0027-8424
1091-6490
issn_str_mv 0027-8424
1091-6490
language English
mega_collection Proceedings of the National Academy of Sciences (CrossRef)
match_str grigliatti1971temperaturesensitivemutationsindrosophilamelanogasterviiithehomeoticmutantssa40a
publishDateSort 1971
publisher Proceedings of the National Academy of Sciences
recordtype ai
record_format ai
series Proceedings of the National Academy of Sciences
source_id 49
title Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_unstemmed Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_full Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_fullStr Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_full_unstemmed Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_short Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_sort temperature-sensitive mutations in <i>drosophila melanogaster</i> , viii. the homeotic mutant, <i> ss <sup>a40a</sup> </i>
topic Multidisciplinary
url http://dx.doi.org/10.1073/pnas.68.6.1307
publishDate 1971
physical 1307-1311
description <jats:p> There exists in <jats:italic>Drosophila</jats:italic> a class of mutations called “homeotic” that cause changes in determination of the imaginal discs. The homeotic mutant, <jats:italic> ss <jats:sup>a40a</jats:sup> </jats:italic> , was found to have a temperature-sensitive transformation of the arista segment of the antennal complex to a tarsus of the leg. In a selected stock penetrance was complete, so that at 29°C normal aristae were produced, whereas at 17°C complete tarsi developed in all flies. “Temperature-shift” studies revealed a temperature-sensitive period in the third larval instar. The temperature-initiated action of <jats:italic> ss <jats:sup>a40a</jats:sup> </jats:italic> does not appear to result from a simple wave or gradient of determination passing through the disc. Shifts up during the temperature-sensitive period yielded leg tissue proximally, which increased distally with progressively later shifts. Shifts down yielded leg tissue at the aristal base, which retreated with later shifts. </jats:p>
container_issue 6
container_start_page 1307
container_title Proceedings of the National Academy of Sciences
container_volume 68
format_de105 Article, E-Article
format_de14 Article, E-Article
format_de15 Article, E-Article
format_de520 Article, E-Article
format_de540 Article, E-Article
format_dech1 Article, E-Article
format_ded117 Article, E-Article
format_degla1 E-Article
format_del152 Buch
format_del189 Article, E-Article
format_dezi4 Article
format_dezwi2 Article, E-Article
format_finc Article, E-Article
format_nrw Article, E-Article
_version_ 1792344427419664392
geogr_code not assigned
last_indexed 2024-03-01T17:07:26.579Z
geogr_code_person not assigned
openURL url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Temperature-Sensitive+Mutations+in++++++++++++Drosophila+melanogaster++++++++++++%2C+VIII.+The+Homeotic+Mutant%2C++++++++++++++++++++++++++ss++++++++++++++a40a++++++++++++&rft.date=1971-06-01&genre=article&issn=1091-6490&volume=68&issue=6&spage=1307&epage=1311&pages=1307-1311&jtitle=Proceedings+of+the+National+Academy+of+Sciences&atitle=Temperature-Sensitive+Mutations+in%0A++++++++++++%3Ci%3EDrosophila+melanogaster%3C%2Fi%3E%0A++++++++++++%2C+VIII.+The+Homeotic+Mutant%2C%0A++++++++++++%3Ci%3E%0A++++++++++++++ss%0A++++++++++++++%3Csup%3Ea40a%3C%2Fsup%3E%0A++++++++++++%3C%2Fi%3E&aulast=Suzuki&aufirst=David+T.&rft_id=info%3Adoi%2F10.1073%2Fpnas.68.6.1307&rft.language%5B0%5D=eng
SOLR
_version_ 1792344427419664392
author Grigliatti, Thomas, Suzuki, David T.
author_facet Grigliatti, Thomas, Suzuki, David T., Grigliatti, Thomas, Suzuki, David T.
author_sort grigliatti, thomas
container_issue 6
container_start_page 1307
container_title Proceedings of the National Academy of Sciences
container_volume 68
description <jats:p> There exists in <jats:italic>Drosophila</jats:italic> a class of mutations called “homeotic” that cause changes in determination of the imaginal discs. The homeotic mutant, <jats:italic> ss <jats:sup>a40a</jats:sup> </jats:italic> , was found to have a temperature-sensitive transformation of the arista segment of the antennal complex to a tarsus of the leg. In a selected stock penetrance was complete, so that at 29°C normal aristae were produced, whereas at 17°C complete tarsi developed in all flies. “Temperature-shift” studies revealed a temperature-sensitive period in the third larval instar. The temperature-initiated action of <jats:italic> ss <jats:sup>a40a</jats:sup> </jats:italic> does not appear to result from a simple wave or gradient of determination passing through the disc. Shifts up during the temperature-sensitive period yielded leg tissue proximally, which increased distally with progressively later shifts. Shifts down yielded leg tissue at the aristal base, which retreated with later shifts. </jats:p>
doi_str_mv 10.1073/pnas.68.6.1307
facet_avail Online, Free
format ElectronicArticle
format_de105 Article, E-Article
format_de14 Article, E-Article
format_de15 Article, E-Article
format_de520 Article, E-Article
format_de540 Article, E-Article
format_dech1 Article, E-Article
format_ded117 Article, E-Article
format_degla1 E-Article
format_del152 Buch
format_del189 Article, E-Article
format_dezi4 Article
format_dezwi2 Article, E-Article
format_finc Article, E-Article
format_nrw Article, E-Article
geogr_code not assigned
geogr_code_person not assigned
id ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA3My9wbmFzLjY4LjYuMTMwNw
imprint Proceedings of the National Academy of Sciences, 1971
imprint_str_mv Proceedings of the National Academy of Sciences, 1971
institution DE-Zi4, DE-Gla1, DE-15, DE-Pl11, DE-Rs1, DE-14, DE-105, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161
issn 0027-8424, 1091-6490
issn_str_mv 0027-8424, 1091-6490
language English
last_indexed 2024-03-01T17:07:26.579Z
match_str grigliatti1971temperaturesensitivemutationsindrosophilamelanogasterviiithehomeoticmutantssa40a
mega_collection Proceedings of the National Academy of Sciences (CrossRef)
physical 1307-1311
publishDate 1971
publishDateSort 1971
publisher Proceedings of the National Academy of Sciences
record_format ai
recordtype ai
series Proceedings of the National Academy of Sciences
source_id 49
spelling Grigliatti, Thomas Suzuki, David T. 0027-8424 1091-6490 Proceedings of the National Academy of Sciences Multidisciplinary http://dx.doi.org/10.1073/pnas.68.6.1307 <jats:p> There exists in <jats:italic>Drosophila</jats:italic> a class of mutations called “homeotic” that cause changes in determination of the imaginal discs. The homeotic mutant, <jats:italic> ss <jats:sup>a40a</jats:sup> </jats:italic> , was found to have a temperature-sensitive transformation of the arista segment of the antennal complex to a tarsus of the leg. In a selected stock penetrance was complete, so that at 29°C normal aristae were produced, whereas at 17°C complete tarsi developed in all flies. “Temperature-shift” studies revealed a temperature-sensitive period in the third larval instar. The temperature-initiated action of <jats:italic> ss <jats:sup>a40a</jats:sup> </jats:italic> does not appear to result from a simple wave or gradient of determination passing through the disc. Shifts up during the temperature-sensitive period yielded leg tissue proximally, which increased distally with progressively later shifts. Shifts down yielded leg tissue at the aristal base, which retreated with later shifts. </jats:p> Temperature-Sensitive Mutations in <i>Drosophila melanogaster</i> , VIII. The Homeotic Mutant, <i> ss <sup>a40a</sup> </i> Proceedings of the National Academy of Sciences
spellingShingle Grigliatti, Thomas, Suzuki, David T., Proceedings of the National Academy of Sciences, Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a , Multidisciplinary
title Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_full Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_fullStr Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_full_unstemmed Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_short Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
title_sort temperature-sensitive mutations in <i>drosophila melanogaster</i> , viii. the homeotic mutant, <i> ss <sup>a40a</sup> </i>
title_unstemmed Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
topic Multidisciplinary
url http://dx.doi.org/10.1073/pnas.68.6.1307