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A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine
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| Zeitschriftentitel: | Yearbook of Medical Informatics |
|---|---|
| Personen und Körperschaften: | , |
| In: | Yearbook of Medical Informatics, 26, 2017, 1, S. 178-187 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Georg Thieme Verlag KG
|
| Schlagwörter: |
| author_facet |
Vamathevan, J. Birney, E. Vamathevan, J. Birney, E. |
|---|---|
| author |
Vamathevan, J. Birney, E. |
| spellingShingle |
Vamathevan, J. Birney, E. Yearbook of Medical Informatics A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine General Medicine |
| author_sort |
vamathevan, j. |
| spelling |
Vamathevan, J. Birney, E. 0943-4747 2364-0502 Georg Thieme Verlag KG General Medicine http://dx.doi.org/10.1055/s-0037-1606500 <jats:title>Summary</jats:title> <jats:p> Objectives: To highlight and provide insights into key developments in translational bioinformatics between 2014 and 2016.</jats:p> <jats:p> Methods: This review describes some of the most influential bioinformatics papers and resources that have been published between 2014 and 2016 as well as the national genome sequencing initiatives that utilize these resources to routinely embed genomic medicine into healthcare. Also discussed are some applications of the secondary use of patient data followed by a comprehensive view of the open challenges and emergent technologies.</jats:p> <jats:p> Results: Although data generation can be performed routinely, analyses and data integration methods still require active research and standardization to improve streamlining of clinical interpretation. The secondary use of patient data has resulted in the development of novel algorithms and has enabled a refined understanding of cellular and phenotypic mechanisms. New data storage and data sharing approaches are required to enable diverse biomedical communities to contribute to genomic discovery.</jats:p> <jats:p> Conclusion: The translation of genomics data into actionable knowledge for use in healthcare is transforming the clinical landscape in an unprecedented way. Exciting and innovative models that bridge the gap between clinical and academic research are set to open up the field of translational bioinformatics for rapid growth in a digital era.</jats:p> A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine Yearbook of Medical Informatics |
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Georg Thieme Verlag KG, 2017 |
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Georg Thieme Verlag KG, 2017 |
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0943-4747 2364-0502 |
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| title |
A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
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A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
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A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
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A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
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A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
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A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
| title_sort |
a review of recent advances in translational bioinformatics: bridges from biology to medicine |
| topic |
General Medicine |
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http://dx.doi.org/10.1055/s-0037-1606500 |
| publishDate |
2017 |
| physical |
178-187 |
| description |
<jats:title>Summary</jats:title>
<jats:p> Objectives: To highlight and provide insights into key developments in translational bioinformatics between 2014 and 2016.</jats:p>
<jats:p> Methods: This review describes some of the most influential bioinformatics papers and resources that have been published between 2014 and 2016 as well as the national genome sequencing initiatives that utilize these resources to routinely embed genomic medicine into healthcare. Also discussed are some applications of the secondary use of patient data followed by a comprehensive view of the open challenges and emergent technologies.</jats:p>
<jats:p> Results: Although data generation can be performed routinely, analyses and data integration methods still require active research and standardization to improve streamlining of clinical interpretation. The secondary use of patient data has resulted in the development of novel algorithms and has enabled a refined understanding of cellular and phenotypic mechanisms. New data storage and data sharing approaches are required to enable diverse biomedical communities to contribute to genomic discovery.</jats:p>
<jats:p> Conclusion: The translation of genomics data into actionable knowledge for use in healthcare is transforming the clinical landscape in an unprecedented way. Exciting and innovative models that bridge the gap between clinical and academic research are set to open up the field of translational bioinformatics for rapid growth in a digital era.</jats:p> |
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| description | <jats:title>Summary</jats:title> <jats:p> Objectives: To highlight and provide insights into key developments in translational bioinformatics between 2014 and 2016.</jats:p> <jats:p> Methods: This review describes some of the most influential bioinformatics papers and resources that have been published between 2014 and 2016 as well as the national genome sequencing initiatives that utilize these resources to routinely embed genomic medicine into healthcare. Also discussed are some applications of the secondary use of patient data followed by a comprehensive view of the open challenges and emergent technologies.</jats:p> <jats:p> Results: Although data generation can be performed routinely, analyses and data integration methods still require active research and standardization to improve streamlining of clinical interpretation. The secondary use of patient data has resulted in the development of novel algorithms and has enabled a refined understanding of cellular and phenotypic mechanisms. New data storage and data sharing approaches are required to enable diverse biomedical communities to contribute to genomic discovery.</jats:p> <jats:p> Conclusion: The translation of genomics data into actionable knowledge for use in healthcare is transforming the clinical landscape in an unprecedented way. Exciting and innovative models that bridge the gap between clinical and academic research are set to open up the field of translational bioinformatics for rapid growth in a digital era.</jats:p> |
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| spelling | Vamathevan, J. Birney, E. 0943-4747 2364-0502 Georg Thieme Verlag KG General Medicine http://dx.doi.org/10.1055/s-0037-1606500 <jats:title>Summary</jats:title> <jats:p> Objectives: To highlight and provide insights into key developments in translational bioinformatics between 2014 and 2016.</jats:p> <jats:p> Methods: This review describes some of the most influential bioinformatics papers and resources that have been published between 2014 and 2016 as well as the national genome sequencing initiatives that utilize these resources to routinely embed genomic medicine into healthcare. Also discussed are some applications of the secondary use of patient data followed by a comprehensive view of the open challenges and emergent technologies.</jats:p> <jats:p> Results: Although data generation can be performed routinely, analyses and data integration methods still require active research and standardization to improve streamlining of clinical interpretation. The secondary use of patient data has resulted in the development of novel algorithms and has enabled a refined understanding of cellular and phenotypic mechanisms. New data storage and data sharing approaches are required to enable diverse biomedical communities to contribute to genomic discovery.</jats:p> <jats:p> Conclusion: The translation of genomics data into actionable knowledge for use in healthcare is transforming the clinical landscape in an unprecedented way. Exciting and innovative models that bridge the gap between clinical and academic research are set to open up the field of translational bioinformatics for rapid growth in a digital era.</jats:p> A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine Yearbook of Medical Informatics |
| spellingShingle | Vamathevan, J., Birney, E., Yearbook of Medical Informatics, A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine, General Medicine |
| title | A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
| title_full | A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
| title_fullStr | A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
| title_full_unstemmed | A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
| title_short | A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
| title_sort | a review of recent advances in translational bioinformatics: bridges from biology to medicine |
| title_unstemmed | A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine |
| topic | General Medicine |
| url | http://dx.doi.org/10.1055/s-0037-1606500 |