Stoichiometric studies of β-alanine transporters in rabbit proximal tubule

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Bibliographische Detailangaben
Zeitschriftentitel:	Biochemical Journal
Personen und Körperschaften:	Jessen, H, Sheikh, M I
In:	Biochemical Journal, 277, 1991, 3, S. 891-894
Format:	E-Article
Sprache:	Englisch
veröffentlicht:	Portland Press Ltd.
Schlagwörter:	Cell Biology Molecular Biology Biochemistry

Details
Zusammenfassung:	<jats:p>The coupling ratio for the transport of beta-alanine and Na+, H+ and Cl- in luminal membrane vesicles isolated from proximal convoluted tubules (pars convoluta) and proximal straight tubules (pars recta) of rabbit kidney was examined. Indirect evidence indicates that 1 H+ and approx. 2 Na+, 1 Cl- (Na(+)-dependent, high-affinity) or 1 Na+ (Na(+)-dependent, low-affinity) are co-transported with beta-alanine in the pars convoluta. In pars recta, the two Na(+)-dependent transporters exhibited the same stoichiometric properties respectively as in pars convoluta.</jats:p>
Umfang:	891-894
ISSN:	0264-6021 1470-8728
DOI:	10.1042/bj2770891