author_facet Paulovic, R P
Anwar, R A
Paulovic, R P
Anwar, R A
author Paulovic, R P
Anwar, R A
spellingShingle Paulovic, R P
Anwar, R A
Biochemical Journal
Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
Cell Biology
Molecular Biology
Biochemistry
author_sort paulovic, r p
spelling Paulovic, R P Anwar, R A 0264-6021 1470-8728 Portland Press Ltd. Cell Biology Molecular Biology Biochemistry http://dx.doi.org/10.1042/bj2610227 <jats:p>The data presented clearly suggest that relative amounts of mRNAs for elastins a, b and c are developmentally regulated in foetal-calf nuchal ligament and aorta and that this regulation is tissue-specific. In nuchal ligament, at earlier stages of foetal development, the relative amounts of mRNAs for elastins a and b are very low. After the foetal age of about 6 months the relative amount of mRNA for elastin b begins to increase. This is followed by an increase in the relative amount of mRNA for elastin a. In aorta, with increasing foetal age, the relative amounts of mRNAs for elastins b and c increase and decrease alternately. The relative amounts of mRNA for elastin a remain low, with only marginal increases with foetal age. A possible self-aggregation role of elastin a in elastogenesis is proposed.</jats:p> Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta Biochemical Journal
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imprint_str_mv Portland Press Ltd., 1989
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source_id 49
title Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_unstemmed Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_full Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_fullStr Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_full_unstemmed Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_short Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_sort developmental regulation of the mrnas for elastins a, b and c in foetal-calf nuchal ligament and aorta
topic Cell Biology
Molecular Biology
Biochemistry
url http://dx.doi.org/10.1042/bj2610227
publishDate 1989
physical 227-232
description <jats:p>The data presented clearly suggest that relative amounts of mRNAs for elastins a, b and c are developmentally regulated in foetal-calf nuchal ligament and aorta and that this regulation is tissue-specific. In nuchal ligament, at earlier stages of foetal development, the relative amounts of mRNAs for elastins a and b are very low. After the foetal age of about 6 months the relative amount of mRNA for elastin b begins to increase. This is followed by an increase in the relative amount of mRNA for elastin a. In aorta, with increasing foetal age, the relative amounts of mRNAs for elastins b and c increase and decrease alternately. The relative amounts of mRNA for elastin a remain low, with only marginal increases with foetal age. A possible self-aggregation role of elastin a in elastogenesis is proposed.</jats:p>
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author Paulovic, R P, Anwar, R A
author_facet Paulovic, R P, Anwar, R A, Paulovic, R P, Anwar, R A
author_sort paulovic, r p
container_issue 1
container_start_page 227
container_title Biochemical Journal
container_volume 261
description <jats:p>The data presented clearly suggest that relative amounts of mRNAs for elastins a, b and c are developmentally regulated in foetal-calf nuchal ligament and aorta and that this regulation is tissue-specific. In nuchal ligament, at earlier stages of foetal development, the relative amounts of mRNAs for elastins a and b are very low. After the foetal age of about 6 months the relative amount of mRNA for elastin b begins to increase. This is followed by an increase in the relative amount of mRNA for elastin a. In aorta, with increasing foetal age, the relative amounts of mRNAs for elastins b and c increase and decrease alternately. The relative amounts of mRNA for elastin a remain low, with only marginal increases with foetal age. A possible self-aggregation role of elastin a in elastogenesis is proposed.</jats:p>
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imprint Portland Press Ltd., 1989
imprint_str_mv Portland Press Ltd., 1989
institution DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Zwi2, DE-Gla1, DE-Zi4
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publisher Portland Press Ltd.
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series Biochemical Journal
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spelling Paulovic, R P Anwar, R A 0264-6021 1470-8728 Portland Press Ltd. Cell Biology Molecular Biology Biochemistry http://dx.doi.org/10.1042/bj2610227 <jats:p>The data presented clearly suggest that relative amounts of mRNAs for elastins a, b and c are developmentally regulated in foetal-calf nuchal ligament and aorta and that this regulation is tissue-specific. In nuchal ligament, at earlier stages of foetal development, the relative amounts of mRNAs for elastins a and b are very low. After the foetal age of about 6 months the relative amount of mRNA for elastin b begins to increase. This is followed by an increase in the relative amount of mRNA for elastin a. In aorta, with increasing foetal age, the relative amounts of mRNAs for elastins b and c increase and decrease alternately. The relative amounts of mRNA for elastin a remain low, with only marginal increases with foetal age. A possible self-aggregation role of elastin a in elastogenesis is proposed.</jats:p> Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta Biochemical Journal
spellingShingle Paulovic, R P, Anwar, R A, Biochemical Journal, Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta, Cell Biology, Molecular Biology, Biochemistry
title Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_full Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_fullStr Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_full_unstemmed Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_short Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_sort developmental regulation of the mrnas for elastins a, b and c in foetal-calf nuchal ligament and aorta
title_unstemmed Developmental regulation of the mRNAs for elastins a, b and c in foetal-calf nuchal ligament and aorta
topic Cell Biology, Molecular Biology, Biochemistry
url http://dx.doi.org/10.1042/bj2610227