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|a An Introduction to the Current Management of Colorectal Cancer in the Era of Personalized Oncology -- Colorectal Cancer Genetics: An Overview of the Actionable Building Blocks -- The Arrival of Next-Generation Sequencing: An Overview of Current Technologies -- Next-Generation Sequencing for Colorectal Cancer Management -- Gut Microbiota, Next-Generation Sequencing, Immune Checkpoint Inhibitors and Colorectal Cancer: How Hot is the Link? -- The Revolution of Liquid Biopsy and Single-Cell Sequencing in the Management of Colorectal Cancer -- Overview of Cost-Effectiveness and Limitations of Next-Generation Sequencing in Colorectal Cancer.
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|a This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers. It critically discusses findings from recent large-scale studies, clinical trials and meta-analyses and offers an introduction to the management of CRC in the era of precision medicine. In CRC, dozens of driver and passenger mutations are associated with the malignant transformation of epithelial cells. Consequently, the book discusses recent advances in our understanding of the genetics of CRC as a biomarker, the advent of NGS technologies in modern genomics, and the impact of NGS technology on the management of CRC. Furthermore, it highlights the potential of NGS in the context of liquid biopsy and single-cell sequencing in CRC, as well as its role in shedding light on the link between gut microbiota, immune-checkpoint blockade and CRC. The book concludes with a chapter on the limitations and cost-effectiveness of NGS in CRC. Given its scope, the book will appeal to all those interested in learning about the potential of NGS in advancing CRC research and patient care. .
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An Introduction to the Current Management of Colorectal Cancer in the Era of Personalized Oncology -- Colorectal Cancer Genetics: An Overview of the Actionable Building Blocks -- The Arrival of Next-Generation Sequencing: An Overview of Current Technologies -- Next-Generation Sequencing for Colorectal Cancer Management -- Gut Microbiota, Next-Generation Sequencing, Immune Checkpoint Inhibitors and Colorectal Cancer: How Hot is the Link? -- The Revolution of Liquid Biopsy and Single-Cell Sequencing in the Management of Colorectal Cancer -- Overview of Cost-Effectiveness and Limitations of Next-Generation Sequencing in Colorectal Cancer., This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers. It critically discusses findings from recent large-scale studies, clinical trials and meta-analyses and offers an introduction to the management of CRC in the era of precision medicine. In CRC, dozens of driver and passenger mutations are associated with the malignant transformation of epithelial cells. Consequently, the book discusses recent advances in our understanding of the genetics of CRC as a biomarker, the advent of NGS technologies in modern genomics, and the impact of NGS technology on the management of CRC. Furthermore, it highlights the potential of NGS in the context of liquid biopsy and single-cell sequencing in CRC, as well as its role in shedding light on the link between gut microbiota, immune-checkpoint blockade and CRC. The book concludes with a chapter on the limitations and cost-effectiveness of NGS in CRC. Given its scope, the book will appeal to all those interested in learning about the potential of NGS in advancing CRC research and patient care. . |
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Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing A Big Chapter in the Tale edited by Khalid El Bairi, 1st ed. 2020., Cham Springer International Publishing 2020., Cham Imprint: Springer 2020., 1 Online-Ressource(XV, 185 p. 26 illus., 25 illus. in color.), Text txt rdacontent, Computermedien c rdamedia, Online-Ressource cr rdacarrier, Springer eBook Collection, An Introduction to the Current Management of Colorectal Cancer in the Era of Personalized Oncology -- Colorectal Cancer Genetics: An Overview of the Actionable Building Blocks -- The Arrival of Next-Generation Sequencing: An Overview of Current Technologies -- Next-Generation Sequencing for Colorectal Cancer Management -- Gut Microbiota, Next-Generation Sequencing, Immune Checkpoint Inhibitors and Colorectal Cancer: How Hot is the Link? -- The Revolution of Liquid Biopsy and Single-Cell Sequencing in the Management of Colorectal Cancer -- Overview of Cost-Effectiveness and Limitations of Next-Generation Sequencing in Colorectal Cancer., This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers. It critically discusses findings from recent large-scale studies, clinical trials and meta-analyses and offers an introduction to the management of CRC in the era of precision medicine. In CRC, dozens of driver and passenger mutations are associated with the malignant transformation of epithelial cells. Consequently, the book discusses recent advances in our understanding of the genetics of CRC as a biomarker, the advent of NGS technologies in modern genomics, and the impact of NGS technology on the management of CRC. Furthermore, it highlights the potential of NGS in the context of liquid biopsy and single-cell sequencing in CRC, as well as its role in shedding light on the link between gut microbiota, immune-checkpoint blockade and CRC. The book concludes with a chapter on the limitations and cost-effectiveness of NGS in CRC. Given its scope, the book will appeal to all those interested in learning about the potential of NGS in advancing CRC research and patient care. ., Cancer research., Genetics., El Bairi, Khalid HerausgeberIn edt, 9783030538200, 9783030538224, 9783030538231, Erscheint auch als Druck-Ausgabe 9783030538200, Erscheint auch als Druck-Ausgabe 9783030538224, Erscheint auch als Druck-Ausgabe 9783030538231, https://doi.org/10.1007/978-3-030-53821-7 X:SPRINGER Resolving-System lizenzpflichtig, https://swbplus.bsz-bw.de/bsz1734622776cov.jpg V:DE-576 X:SPRINGER image/jpeg 20210930145526 Cover, https://doi.org/10.1007/978-3-030-53821-7 DE-14, DE-14 epn:3767010534 2020-10-05T11:07:58Z, DE-15 epn:4005468160 del:202302240140, https://doi.org/10.1007/978-3-030-53821-7 DE-Ch1, DE-Ch1 epn:3767010585 2020-10-05T11:07:59Z, https://doi.org/10.1007/978-3-030-53821-7 DE-Zwi2, DE-Zwi2 epn:3767010593 2020-10-05T11:07:59Z |
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Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing: A Big Chapter in the Tale, An Introduction to the Current Management of Colorectal Cancer in the Era of Personalized Oncology -- Colorectal Cancer Genetics: An Overview of the Actionable Building Blocks -- The Arrival of Next-Generation Sequencing: An Overview of Current Technologies -- Next-Generation Sequencing for Colorectal Cancer Management -- Gut Microbiota, Next-Generation Sequencing, Immune Checkpoint Inhibitors and Colorectal Cancer: How Hot is the Link? -- The Revolution of Liquid Biopsy and Single-Cell Sequencing in the Management of Colorectal Cancer -- Overview of Cost-Effectiveness and Limitations of Next-Generation Sequencing in Colorectal Cancer., This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers. It critically discusses findings from recent large-scale studies, clinical trials and meta-analyses and offers an introduction to the management of CRC in the era of precision medicine. In CRC, dozens of driver and passenger mutations are associated with the malignant transformation of epithelial cells. Consequently, the book discusses recent advances in our understanding of the genetics of CRC as a biomarker, the advent of NGS technologies in modern genomics, and the impact of NGS technology on the management of CRC. Furthermore, it highlights the potential of NGS in the context of liquid biopsy and single-cell sequencing in CRC, as well as its role in shedding light on the link between gut microbiota, immune-checkpoint blockade and CRC. The book concludes with a chapter on the limitations and cost-effectiveness of NGS in CRC. Given its scope, the book will appeal to all those interested in learning about the potential of NGS in advancing CRC research and patient care. ., Cancer research., Genetics. |
| title |
Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing: A Big Chapter in the Tale |
| title_auth |
Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing A Big Chapter in the Tale |
| title_full |
Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing A Big Chapter in the Tale edited by Khalid El Bairi |
| title_fullStr |
Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing A Big Chapter in the Tale edited by Khalid El Bairi |
| title_full_unstemmed |
Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing A Big Chapter in the Tale edited by Khalid El Bairi |
| title_short |
Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing |
| title_sort |
illuminating colorectal cancer genomics by next-generation sequencing a big chapter in the tale |
| title_sub |
A Big Chapter in the Tale |
| title_unstemmed |
Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing: A Big Chapter in the Tale |
| topic |
Cancer research., Genetics. |
| topic_facet |
Cancer research., Genetics. |
| url |
https://doi.org/10.1007/978-3-030-53821-7, https://swbplus.bsz-bw.de/bsz1734622776cov.jpg |
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AT elbairikhalid illuminatingcolorectalcancergenomicsbynextgenerationsequencingabigchapterinthetale |
