Eintrag weiter verarbeiten
Notch Signaling in Embryology and Cancer: Molecular Biology of Notch Signaling
Gespeichert in:
| Personen und Körperschaften: | , |
|---|---|
| Titel: | Notch Signaling in Embryology and Cancer: Molecular Biology of Notch Signaling/ edited by Jörg Reichrath, Sandra Reichrath. |
| Ausgabe: | 2nd ed. 2020. |
| Format: | E-Book |
| Sprache: | Englisch |
| veröffentlicht: |
Cham
Springer International Publishing
2020.
Cham Imprint: Springer 2020. |
| Gesamtaufnahme: |
Advances in Experimental Medicine and Biology Springer eBook Collection |
| Schlagwörter: | |
| Quelle: | Verbunddaten SWB |
| LEADER | 04930cam a22006852 4500 | ||
|---|---|---|---|
| 001 | 0-1691528501 | ||
| 003 | DE-627 | ||
| 005 | 20220729055439.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200304s2020 gw |||||o 00| ||eng c | ||
| 020 | |a 9783030364229 |9 978-3-030-36422-9 | ||
| 024 | 7 | |a 10.1007/978-3-030-36422-9 |2 doi | |
| 035 | |a (DE-627)1691528501 | ||
| 035 | |a (DE-599)KEP050173677 | ||
| 035 | |a (DE-He213)978-3-030-36422-9 | ||
| 035 | |a (EBP)050173677 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 044 | |c XA-DE | ||
| 082 | 0 | |a 614.5999 |2 23 | |
| 084 | |a MJCL |2 bicssc | ||
| 084 | |a MED062000 |2 bisacsh | ||
| 245 | 1 | 0 | |a Notch Signaling in Embryology and Cancer |b Molecular Biology of Notch Signaling |c edited by Jörg Reichrath, Sandra Reichrath. |
| 250 | |a 2nd ed. 2020. | ||
| 264 | 1 | |a Cham |b Springer International Publishing |c 2020. | |
| 264 | 1 | |a Cham |b Imprint: Springer |c 2020. | |
| 300 | |a 1 Online-Ressource(XIII, 172 p. 32 illus., 31 illus. in color.) | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 490 | 0 | |a Advances in Experimental Medicine and Biology |v 1227 | |
| 490 | 0 | |a Springer eBook Collection | |
| 520 | |a Challenge and Promise: A Snap-Shot on the Molecular Biology of Notch Signaling -- Overview of Basic Mechanisms of Notch Signaling in Development and Disease -- Ligand-induced cis-inhibition of Notch signaling: the role of an extracellular region of Serrate -- Phosphorylation and proteolytic cleavage of Notch in canonical and non-canonical Notch signaling -- Maheshvara a conserved RNA helicase regulates Notch signaling in Drosophila melanogaster -- Molecular Regulation of Notch Signaling by Gremlin -- Regulation of Notch Signaling in Drosophila melanogaster: the role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex -- Interaction of Long Non-Coding RNAs and Notch Signaling: Implications for Tissue Homeostasis Loss -- Insulin–dependent non-canonical activation of Notch in Drosophila: a story of Notch-induced muscle stem cells proliferation -- Molecular mechanisms of Notch signaling in lymphoid cell lineages development: NF-κB and beyond -- Index. | ||
| 520 | |a This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books – Notch Signaling in Embryology and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students. | ||
| 650 | 0 | |a Cancer research. | |
| 650 | 0 | |a Cell biology. | |
| 650 | 0 | |a Embryology. | |
| 700 | 1 | |a Reichrath, Jörg |e HerausgeberIn |4 edt | |
| 700 | 1 | |a Reichrath, Sandra |e HerausgeberIn |4 edt | |
| 776 | 1 | |z 9783030364212 | |
| 776 | 1 | |z 9783030364236 | |
| 776 | 1 | |z 9783030364243 | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9783030364212 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9783030364236 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9783030364243 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-030-36422-9 |m X:SPRINGER |x Resolving-System |z lizenzpflichtig |
| 912 | |a ZDB-2-SBL |b 2020 | ||
| 912 | |a ZDB-2-SEB | ||
| 912 | |a ZDB-2-SXB |b 2020 | ||
| 951 | |a BO | ||
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-030-36422-9 |9 DE-14 |
| 852 | |a DE-14 |x epn:3603601602 |z 2020-03-04T12:03:49Z | ||
| 852 | |d DE-15 |x epn:4005473148 del:202302240140 | ||
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-030-36422-9 |9 DE-Ch1 |
| 852 | |a DE-Ch1 |x epn:3603601653 |z 2020-03-04T12:03:50Z | ||
| 975 | |o Springer E-Book | ||
| 975 | |k Elektronischer Volltext - Campuslizenz | ||
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-030-36422-9 |9 DE-Zwi2 |
| 852 | |a DE-Zwi2 |x epn:3603601661 |z 2020-03-04T12:03:50Z | ||
| 980 | |a 1691528501 |b 0 |k 1691528501 | ||
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Notch+Signaling+in+Embryology+and+Cancer%3A+Molecular+Biology+of+Notch+Signaling&rft.date=2020.&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Notch+Signaling+in+Embryology+and+Cancer%3A+Molecular+Biology+of+Notch+Signaling&rft.series=Advances+in+Experimental+Medicine+and+Biology+%3B+1227&rft.au=&rft.pub=Springer+International+Publishing&rft.edition=2nd+ed.+2020.&rft.isbn=3030364224 |
|---|
| _version_ | 1795509386237444096 |
|---|---|
| author2 | Reichrath, Jörg, Reichrath, Sandra |
| author2_role | edt, edt |
| author2_variant | j r jr, s r sr |
| author_facet | Reichrath, Jörg, Reichrath, Sandra |
| collection | ZDB-2-SBL, ZDB-2-SEB, ZDB-2-SXB |
| contents | Challenge and Promise: A Snap-Shot on the Molecular Biology of Notch Signaling -- Overview of Basic Mechanisms of Notch Signaling in Development and Disease -- Ligand-induced cis-inhibition of Notch signaling: the role of an extracellular region of Serrate -- Phosphorylation and proteolytic cleavage of Notch in canonical and non-canonical Notch signaling -- Maheshvara a conserved RNA helicase regulates Notch signaling in Drosophila melanogaster -- Molecular Regulation of Notch Signaling by Gremlin -- Regulation of Notch Signaling in Drosophila melanogaster: the role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex -- Interaction of Long Non-Coding RNAs and Notch Signaling: Implications for Tissue Homeostasis Loss -- Insulin–dependent non-canonical activation of Notch in Drosophila: a story of Notch-induced muscle stem cells proliferation -- Molecular mechanisms of Notch signaling in lymphoid cell lineages development: NF-κB and beyond -- Index., This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books – Notch Signaling in Embryology and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students. |
| ctrlnum | (DE-627)1691528501, (DE-599)KEP050173677, (DE-He213)978-3-030-36422-9, (EBP)050173677 |
| dech1_date | 2020-03-04T12:03:50Z |
| dewey-full | 614.5999 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 614 - Forensic medicine; incidence of disease |
| dewey-raw | 614.5999 |
| dewey-search | 614.5999 |
| dewey-sort | 3614.5999 |
| dewey-tens | 610 - Medicine and health |
| doi_str_mv | 10.1007/978-3-030-36422-9 |
| edition | 2nd ed. 2020. |
| facet_912a | ZDB-2-SBL, ZDB-2-SEB, ZDB-2-SXB |
| facet_avail | Online |
| finc_class_facet | Technik, Medizin |
| fincclass_txtF_mv | medicine |
| format | eBook |
| format_access_txtF_mv | Book, E-Book |
| format_de105 | Ebook |
| format_de14 | Book, E-Book |
| format_de15 | Book, E-Book |
| format_del152 | Buch |
| format_detail_txtF_mv | text-online-monograph-independent |
| format_dezi4 | e-Book |
| format_finc | Book, E-Book |
| format_legacy | ElectronicBook |
| format_legacy_nrw | Book, E-Book |
| format_nrw | Book, E-Book |
| format_strict_txtF_mv | E-Book |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | 0-1691528501 |
| illustrated | Not Illustrated |
| imprint | Cham, Springer International Publishing, 2020 |
| imprint_str_mv | Cham: Springer International Publishing, 2020., Cham: Imprint: Springer, 2020. |
| institution | DE-14, DE-Zwi2, DE-Ch1 |
| is_hierarchy_id | |
| is_hierarchy_title | |
| isbn | 9783030364229 |
| isbn_isn_mv | 9783030364212, 9783030364236, 9783030364243 |
| kxp_id_str | 1691528501 |
| language | English |
| last_indexed | 2024-04-05T15:33:03.584Z |
| local_heading_facet_dezwi2 | Cancer research., Cell biology., Embryology. |
| marc024a_ct_mv | 10.1007/978-3-030-36422-9 |
| marc_error | [geogr_code]Unable to make public java.lang.AbstractStringBuilder java.lang.AbstractStringBuilder.append(java.lang.String) accessible: module java.base does not "opens java.lang" to unnamed module @7838f2f1 |
| match_str | reichrath2020notchsignalinginembryologyandcancermolecularbiologyofnotchsignaling |
| mega_collection | Verbunddaten SWB |
| physical | 1 Online-Ressource(XIII, 172 p. 32 illus., 31 illus. in color.) |
| publishDate | 2020., , 2020. |
| publishDateSort | 2020 |
| publishPlace | Cham, ; Cham |
| publisher | Springer International Publishing, : Imprint: Springer |
| record_format | marcfinc |
| record_id | 1691528501 |
| recordtype | marcfinc |
| rvk_facet | No subject assigned |
| series2 | Advances in Experimental Medicine and Biology ; 1227, Springer eBook Collection |
| source_id | 0 |
| spelling | Notch Signaling in Embryology and Cancer Molecular Biology of Notch Signaling edited by Jörg Reichrath, Sandra Reichrath., 2nd ed. 2020., Cham Springer International Publishing 2020., Cham Imprint: Springer 2020., 1 Online-Ressource(XIII, 172 p. 32 illus., 31 illus. in color.), Text txt rdacontent, Computermedien c rdamedia, Online-Ressource cr rdacarrier, Advances in Experimental Medicine and Biology 1227, Springer eBook Collection, Challenge and Promise: A Snap-Shot on the Molecular Biology of Notch Signaling -- Overview of Basic Mechanisms of Notch Signaling in Development and Disease -- Ligand-induced cis-inhibition of Notch signaling: the role of an extracellular region of Serrate -- Phosphorylation and proteolytic cleavage of Notch in canonical and non-canonical Notch signaling -- Maheshvara a conserved RNA helicase regulates Notch signaling in Drosophila melanogaster -- Molecular Regulation of Notch Signaling by Gremlin -- Regulation of Notch Signaling in Drosophila melanogaster: the role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex -- Interaction of Long Non-Coding RNAs and Notch Signaling: Implications for Tissue Homeostasis Loss -- Insulin–dependent non-canonical activation of Notch in Drosophila: a story of Notch-induced muscle stem cells proliferation -- Molecular mechanisms of Notch signaling in lymphoid cell lineages development: NF-κB and beyond -- Index., This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books – Notch Signaling in Embryology and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students., Cancer research., Cell biology., Embryology., Reichrath, Jörg HerausgeberIn edt, Reichrath, Sandra HerausgeberIn edt, 9783030364212, 9783030364236, 9783030364243, Erscheint auch als Druck-Ausgabe 9783030364212, Erscheint auch als Druck-Ausgabe 9783030364236, Erscheint auch als Druck-Ausgabe 9783030364243, https://doi.org/10.1007/978-3-030-36422-9 X:SPRINGER Resolving-System lizenzpflichtig, https://doi.org/10.1007/978-3-030-36422-9 DE-14, DE-14 epn:3603601602 2020-03-04T12:03:49Z, DE-15 epn:4005473148 del:202302240140, https://doi.org/10.1007/978-3-030-36422-9 DE-Ch1, DE-Ch1 epn:3603601653 2020-03-04T12:03:50Z, https://doi.org/10.1007/978-3-030-36422-9 DE-Zwi2, DE-Zwi2 epn:3603601661 2020-03-04T12:03:50Z |
| spellingShingle | Notch Signaling in Embryology and Cancer: Molecular Biology of Notch Signaling, Challenge and Promise: A Snap-Shot on the Molecular Biology of Notch Signaling -- Overview of Basic Mechanisms of Notch Signaling in Development and Disease -- Ligand-induced cis-inhibition of Notch signaling: the role of an extracellular region of Serrate -- Phosphorylation and proteolytic cleavage of Notch in canonical and non-canonical Notch signaling -- Maheshvara a conserved RNA helicase regulates Notch signaling in Drosophila melanogaster -- Molecular Regulation of Notch Signaling by Gremlin -- Regulation of Notch Signaling in Drosophila melanogaster: the role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex -- Interaction of Long Non-Coding RNAs and Notch Signaling: Implications for Tissue Homeostasis Loss -- Insulin–dependent non-canonical activation of Notch in Drosophila: a story of Notch-induced muscle stem cells proliferation -- Molecular mechanisms of Notch signaling in lymphoid cell lineages development: NF-κB and beyond -- Index., This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books – Notch Signaling in Embryology and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students., Cancer research., Cell biology., Embryology. |
| title | Notch Signaling in Embryology and Cancer: Molecular Biology of Notch Signaling |
| title_auth | Notch Signaling in Embryology and Cancer Molecular Biology of Notch Signaling |
| title_full | Notch Signaling in Embryology and Cancer Molecular Biology of Notch Signaling edited by Jörg Reichrath, Sandra Reichrath. |
| title_fullStr | Notch Signaling in Embryology and Cancer Molecular Biology of Notch Signaling edited by Jörg Reichrath, Sandra Reichrath. |
| title_full_unstemmed | Notch Signaling in Embryology and Cancer Molecular Biology of Notch Signaling edited by Jörg Reichrath, Sandra Reichrath. |
| title_short | Notch Signaling in Embryology and Cancer |
| title_sort | notch signaling in embryology and cancer molecular biology of notch signaling |
| title_sub | Molecular Biology of Notch Signaling |
| title_unstemmed | Notch Signaling in Embryology and Cancer: Molecular Biology of Notch Signaling |
| topic | Cancer research., Cell biology., Embryology. |
| topic_facet | Cancer research., Cell biology., Embryology. |
| url | https://doi.org/10.1007/978-3-030-36422-9 |
| work_keys_str_mv | AT reichrathjorg notchsignalinginembryologyandcancermolecularbiologyofnotchsignaling, AT reichrathsandra notchsignalinginembryologyandcancermolecularbiologyofnotchsignaling |