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Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation
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| Veröffentlicht in: | Scientific reports 8(2018) Artikel-Nummer 8546, 7 Seiten |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , |
| Titel: | Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation/ Bastian Schmack, Leonie Grossekettler, Alexander Weymann, Joel Schamroth, Anton Sabashnikov, Philip W. Raake, Aron F. Popov, Ashham Mansur, Matthias Karck, Vedat Schwenger & Arjang Ruhparwar |
| Format: | E-Book-Kapitel |
| Sprache: | Englisch |
| veröffentlicht: |
04 June 2018
|
| Gesamtaufnahme: |
: Scientific reports, 8(2018) Artikel-Nummer 8546, 7 Seiten
, volume:8 |
| Quelle: | Verbunddaten SWB Lizenzfreie Online-Ressourcen |
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| 245 | 1 | 0 | |a Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation |c Bastian Schmack, Leonie Grossekettler, Alexander Weymann, Joel Schamroth, Anton Sabashnikov, Philip W. Raake, Aron F. Popov, Ashham Mansur, Matthias Karck, Vedat Schwenger & Arjang Ruhparwar |
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| 520 | |a End-stage heart failure (HF) is associated with renal failure (RF). This study aimed to determine the prognostic influence of RF and post-operative hemodialysis on short-term survival following left ventricular assist device (LVAD) implantation. This retrospective study includes 68 patients undergoing LVAD treatment. Kidney function was recorded prior to LVAD implantation, immediately afterwards and after 30 days, noting the need for hemodialysis. Median pre-operative Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) classification was 3.47 ± 1.08. 30 days after implantation there was a significant improvement of estimated glomerular filtration rate (eGFR) and reduction of blood urea nitrogen (BUN). Of pre-operative RF parameters, BUN was associated with increased mortality and need for early post-operative hemodialysis. Post-operative hemodialysis was associated with significantly lower short-term survival, while pre-operative hemodialysis did not impact mortality. Post-operative acute kidney injury (AKI) requiring hemodialysis can be regarded as a strong negative prognostic marker for short-term survival. The absence of a clear correlation between most routine RF parameters and survival or the need for early post-operative hemodialysis calls into question the predictive value of pre-operative RF. The negative association of only post-operative hemodialysis on short-term survival emphasises the impact of the occurrence of AKI. | ||
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| contents | End-stage heart failure (HF) is associated with renal failure (RF). This study aimed to determine the prognostic influence of RF and post-operative hemodialysis on short-term survival following left ventricular assist device (LVAD) implantation. This retrospective study includes 68 patients undergoing LVAD treatment. Kidney function was recorded prior to LVAD implantation, immediately afterwards and after 30 days, noting the need for hemodialysis. Median pre-operative Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) classification was 3.47 ± 1.08. 30 days after implantation there was a significant improvement of estimated glomerular filtration rate (eGFR) and reduction of blood urea nitrogen (BUN). Of pre-operative RF parameters, BUN was associated with increased mortality and need for early post-operative hemodialysis. Post-operative hemodialysis was associated with significantly lower short-term survival, while pre-operative hemodialysis did not impact mortality. Post-operative acute kidney injury (AKI) requiring hemodialysis can be regarded as a strong negative prognostic marker for short-term survival. The absence of a clear correlation between most routine RF parameters and survival or the need for early post-operative hemodialysis calls into question the predictive value of pre-operative RF. The negative association of only post-operative hemodialysis on short-term survival emphasises the impact of the occurrence of AKI. |
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| spelling | Schmack, Bastian 1981- VerfasserIn (DE-588)142852961 (DE-627)640546293 (DE-576)333714067 aut, Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation Bastian Schmack, Leonie Grossekettler, Alexander Weymann, Joel Schamroth, Anton Sabashnikov, Philip W. Raake, Aron F. Popov, Ashham Mansur, Matthias Karck, Vedat Schwenger & Arjang Ruhparwar, 04 June 2018, 7, Text txt rdacontent, Computermedien c rdamedia, Online-Ressource cr rdacarrier, Gesehen am 06.08.2018, End-stage heart failure (HF) is associated with renal failure (RF). This study aimed to determine the prognostic influence of RF and post-operative hemodialysis on short-term survival following left ventricular assist device (LVAD) implantation. This retrospective study includes 68 patients undergoing LVAD treatment. Kidney function was recorded prior to LVAD implantation, immediately afterwards and after 30 days, noting the need for hemodialysis. Median pre-operative Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) classification was 3.47 ± 1.08. 30 days after implantation there was a significant improvement of estimated glomerular filtration rate (eGFR) and reduction of blood urea nitrogen (BUN). Of pre-operative RF parameters, BUN was associated with increased mortality and need for early post-operative hemodialysis. Post-operative hemodialysis was associated with significantly lower short-term survival, while pre-operative hemodialysis did not impact mortality. Post-operative acute kidney injury (AKI) requiring hemodialysis can be regarded as a strong negative prognostic marker for short-term survival. The absence of a clear correlation between most routine RF parameters and survival or the need for early post-operative hemodialysis calls into question the predictive value of pre-operative RF. The negative association of only post-operative hemodialysis on short-term survival emphasises the impact of the occurrence of AKI., Grossekettler, Leonie VerfasserIn (DE-588)1163962104 (DE-627)1028338783 (DE-576)508272173 aut, Weymann, Alexander VerfasserIn (DE-588)1051122651 (DE-627)785827102 (DE-576)40592657X aut, Schamroth, Joel VerfasserIn aut, Sabashnikov, Anton VerfasserIn aut, Raake, Philip 1975- VerfasserIn (DE-588)129151246 (DE-627)390021725 (DE-576)297510568 aut, Popov, Aron F. VerfasserIn aut, Mansur, Ashham VerfasserIn aut, Karck, Matthias 1961- VerfasserIn (DE-588)130833525 (DE-627)505909340 (DE-576)298366169 aut, Schwenger, Vedat VerfasserIn (DE-588)1022867652 (DE-627)717320197 (DE-576)176592237 aut, Ruhparwar, Arjang VerfasserIn (DE-588)138079021 (DE-627)599042591 (DE-576)306325926 aut, Enthalten in Scientific reports [London] : Macmillan Publishers Limited, part of Springer Nature, 2011 8(2018) Artikel-Nummer 8546, 7 Seiten Online-Ressource (DE-627)663366712 (DE-600)2615211-3 (DE-576)346641179 2045-2322 nnns, volume:8 year:2018 extent:7, http://dx.doi.org/10.1038/s41598-018-26515-0 Verlag Resolving-System kostenfrei Volltext, https://www.nature.com/articles/s41598-018-26515-0 Verlag kostenfrei Volltext, http://dx.doi.org/10.1038/s41598-018-26515-0 LFER, LFER 2018-08-13T00:00:00Z |
| spellingShingle | Schmack, Bastian, Grossekettler, Leonie, Weymann, Alexander, Schamroth, Joel, Sabashnikov, Anton, Raake, Philip, Popov, Aron F., Mansur, Ashham, Karck, Matthias, Schwenger, Vedat, Ruhparwar, Arjang, Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation, End-stage heart failure (HF) is associated with renal failure (RF). This study aimed to determine the prognostic influence of RF and post-operative hemodialysis on short-term survival following left ventricular assist device (LVAD) implantation. This retrospective study includes 68 patients undergoing LVAD treatment. Kidney function was recorded prior to LVAD implantation, immediately afterwards and after 30 days, noting the need for hemodialysis. Median pre-operative Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) classification was 3.47 ± 1.08. 30 days after implantation there was a significant improvement of estimated glomerular filtration rate (eGFR) and reduction of blood urea nitrogen (BUN). Of pre-operative RF parameters, BUN was associated with increased mortality and need for early post-operative hemodialysis. Post-operative hemodialysis was associated with significantly lower short-term survival, while pre-operative hemodialysis did not impact mortality. Post-operative acute kidney injury (AKI) requiring hemodialysis can be regarded as a strong negative prognostic marker for short-term survival. The absence of a clear correlation between most routine RF parameters and survival or the need for early post-operative hemodialysis calls into question the predictive value of pre-operative RF. The negative association of only post-operative hemodialysis on short-term survival emphasises the impact of the occurrence of AKI. |
| swb_id_str | 508274257 |
| title | Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation |
| title_auth | Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation |
| title_full | Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation Bastian Schmack, Leonie Grossekettler, Alexander Weymann, Joel Schamroth, Anton Sabashnikov, Philip W. Raake, Aron F. Popov, Ashham Mansur, Matthias Karck, Vedat Schwenger & Arjang Ruhparwar |
| title_fullStr | Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation Bastian Schmack, Leonie Grossekettler, Alexander Weymann, Joel Schamroth, Anton Sabashnikov, Philip W. Raake, Aron F. Popov, Ashham Mansur, Matthias Karck, Vedat Schwenger & Arjang Ruhparwar |
| title_full_unstemmed | Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation Bastian Schmack, Leonie Grossekettler, Alexander Weymann, Joel Schamroth, Anton Sabashnikov, Philip W. Raake, Aron F. Popov, Ashham Mansur, Matthias Karck, Vedat Schwenger & Arjang Ruhparwar |
| title_in_hierarchy | Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation / Bastian Schmack, Leonie Grossekettler, Alexander Weymann, Joel Schamroth, Anton Sabashnikov, Philip W. Raake, Aron F. Popov, Ashham Mansur, Matthias Karck, Vedat Schwenger & Arjang Ruhparwar, |
| title_short | Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation |
| title_sort | prognostic relevance of hemodialysis for short term survival in patients after lvad implantation |
| url | http://dx.doi.org/10.1038/s41598-018-26515-0, https://www.nature.com/articles/s41598-018-26515-0 |