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Cholesterol metabolism in T cells
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| Veröffentlicht in: | Frontiers in immunology 8(2017) Artikel-Nummer 1664, 8 Seiten |
|---|---|
| Personen und Körperschaften: | |
| Titel: | Cholesterol metabolism in T cells/ Andreas Bietz, Hengyu Zhu, Manman Xue and Chenqi Xu |
| Format: | E-Book-Kapitel |
| Sprache: | Englisch |
| veröffentlicht: |
27 November 2017
|
| Gesamtaufnahme: |
: Frontiers in immunology, 8(2017) Artikel-Nummer 1664, 8 Seiten
, volume:8 |
| Schlagwörter: | |
| Quelle: | Verbunddaten SWB Lizenzfreie Online-Ressourcen |
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| 520 | |a Compartmentalization is arguably one of the first critical criteria for the existence of cell-based life. All reactions in cells rely on spatial control of their components, as well as long term storage of encoded information. The lipid bilayer and its associated organelles form the foundation for all reactions and structures in the cell. Sterols (mainly cholesterol in mammalian cells), phospholipids, sphingolipids, and proteins form an integral part in maintaining optimal stability and fluidity of the membrane. In this review, cholesterol metabolism will be examined in general. Further, the importance of the cholesterol pathway in activation and function of T cells as well as the methods to modulate this pathway in disease contexts will be discussed. | ||
| 650 | 4 | |a Cholesterol | |
| 650 | 4 | |a Disease | |
| 650 | 4 | |a Immunomodulation | |
| 650 | 4 | |a Metabolism | |
| 650 | 4 | |a T cell | |
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| contents | Compartmentalization is arguably one of the first critical criteria for the existence of cell-based life. All reactions in cells rely on spatial control of their components, as well as long term storage of encoded information. The lipid bilayer and its associated organelles form the foundation for all reactions and structures in the cell. Sterols (mainly cholesterol in mammalian cells), phospholipids, sphingolipids, and proteins form an integral part in maintaining optimal stability and fluidity of the membrane. In this review, cholesterol metabolism will be examined in general. Further, the importance of the cholesterol pathway in activation and function of T cells as well as the methods to modulate this pathway in disease contexts will be discussed. |
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| spelling | Bietz, Andreas VerfasserIn (DE-588)1162960019 (DE-627)1027048595 (DE-576)507701445 aut, Cholesterol metabolism in T cells Andreas Bietz, Hengyu Zhu, Manman Xue and Chenqi Xu, 27 November 2017, 8, Text txt rdacontent, Computermedien c rdamedia, Online-Ressource cr rdacarrier, Gesehen am 18.07.2018, Compartmentalization is arguably one of the first critical criteria for the existence of cell-based life. All reactions in cells rely on spatial control of their components, as well as long term storage of encoded information. The lipid bilayer and its associated organelles form the foundation for all reactions and structures in the cell. Sterols (mainly cholesterol in mammalian cells), phospholipids, sphingolipids, and proteins form an integral part in maintaining optimal stability and fluidity of the membrane. In this review, cholesterol metabolism will be examined in general. Further, the importance of the cholesterol pathway in activation and function of T cells as well as the methods to modulate this pathway in disease contexts will be discussed., Cholesterol, Disease, Immunomodulation, Metabolism, T cell, Enthalten in Frontiers in immunology Lausanne : Frontiers Media, 2010 8(2017) Artikel-Nummer 1664, 8 Seiten Online-Ressource (DE-627)657998354 (DE-600)2606827-8 (DE-576)343624834 1664-3224 nnns, volume:8 year:2017 extent:8, http://dx.doi.org/10.3389/fimmu.2017.01664 Verlag Resolving-System kostenfrei Volltext, https://www.frontiersin.org/articles/10.3389/fimmu.2017.01664/full Verlag kostenfrei Volltext, http://dx.doi.org/10.3389/fimmu.2017.01664 LFER, LFER 2018-08-13T00:00:00Z |
| spellingShingle | Bietz, Andreas, Cholesterol metabolism in T cells, Compartmentalization is arguably one of the first critical criteria for the existence of cell-based life. All reactions in cells rely on spatial control of their components, as well as long term storage of encoded information. The lipid bilayer and its associated organelles form the foundation for all reactions and structures in the cell. Sterols (mainly cholesterol in mammalian cells), phospholipids, sphingolipids, and proteins form an integral part in maintaining optimal stability and fluidity of the membrane. In this review, cholesterol metabolism will be examined in general. Further, the importance of the cholesterol pathway in activation and function of T cells as well as the methods to modulate this pathway in disease contexts will be discussed., Cholesterol, Disease, Immunomodulation, Metabolism, T cell |
| swb_id_str | 507701658 |
| title | Cholesterol metabolism in T cells |
| title_auth | Cholesterol metabolism in T cells |
| title_full | Cholesterol metabolism in T cells Andreas Bietz, Hengyu Zhu, Manman Xue and Chenqi Xu |
| title_fullStr | Cholesterol metabolism in T cells Andreas Bietz, Hengyu Zhu, Manman Xue and Chenqi Xu |
| title_full_unstemmed | Cholesterol metabolism in T cells Andreas Bietz, Hengyu Zhu, Manman Xue and Chenqi Xu |
| title_in_hierarchy | Cholesterol metabolism in T cells / Andreas Bietz, Hengyu Zhu, Manman Xue and Chenqi Xu, |
| title_short | Cholesterol metabolism in T cells |
| title_sort | cholesterol metabolism in t cells |
| topic | Cholesterol, Disease, Immunomodulation, Metabolism, T cell |
| topic_facet | Cholesterol, Disease, Immunomodulation, Metabolism, T cell |
| url | http://dx.doi.org/10.3389/fimmu.2017.01664, https://www.frontiersin.org/articles/10.3389/fimmu.2017.01664/full |