Eintrag weiter verarbeiten
Mechanistic and structural characterization of thiamine diphosphate dependent enzyme transketolases from human and (E.coli)
Gespeichert in:
| Personen und Körperschaften: | , , , |
|---|---|
| Titel: | Mechanistic and structural characterization of thiamine diphosphate dependent enzyme transketolases from human and (E.coli)/ vorgelegt von Shao-Bo Dai |
| Hochschulschriftenvermerk: | Dissertation, Georg-August-Universität Göttingen, 2017 |
| Format: | E-Book Hochschulschrift |
| Sprache: | Englisch |
| veröffentlicht: |
Göttingen
2017
|
| Schlagwörter: | |
| Erscheint auch als: | Dai, Shao-Bo, Mechanistic and structural characterization of thiamine diphosphate dependent enzyme transketolases from human and (E.coli), Göttingen, 2017, 1 Online-Ressource |
| Quelle: | Verbunddaten SWB Lizenzfreie Online-Ressourcen |
| Zusammenfassung: | Thiamine diphosphate (ThDP) dependent enzymes are essential in the metabolism of biological systems, and many of these enzymes are extensively used in the biosynthetic of valuable compounds. In this regard, a comprehensive study of the catalytic mechanism of this family of enzymes are demanding, especially high resolution structural information. In this thesis, we present the mechanistic study of transketolase, one representative ThDP dependent enzyme, from several different aspects. First we show that a low barrier hydrogen bond (LBHB) is present in the crystal structure of human transketo... |
|---|---|
| Umfang: | 1 Online-Ressource; Illustrationen, Diagramme |