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Fraumeni, J F
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Fraumeni, J F
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Fraumeni, J F
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Fraumeni, J F
American Journal of Public Health
Late effects following isoniazid therapy.
Public Health, Environmental and Occupational Health
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spelling Boice, J D Fraumeni, J F 0090-0036 1541-0048 American Public Health Association Public Health, Environmental and Occupational Health http://dx.doi.org/10.2105/ajph.70.9.987 <jats:p> Amont 338 women treated in Massachusetts with isoniazid (isonicotinic acid hydrazide = INH) for pulmonary tuberculosis, no excess cancer deaths occurred (8 observed vs 8.3 expected) after 23 years (12.9 mean) of follow-up. There was an excess of cancer deaths (54 vs 35.7) among 1,090 patients who did not receive INH, partly due to radiogenic breast cancer resulting from multiple chest fluoroscopies to monitor pneumothorax. Increased deaths from liver cirrhosis (5 vs 0.8) were observed following INH use, suggesting that chronic as well as acute liver disease complicate this treatment. </jats:p> Late effects following isoniazid therapy. American Journal of Public Health
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title Late effects following isoniazid therapy.
title_unstemmed Late effects following isoniazid therapy.
title_full Late effects following isoniazid therapy.
title_fullStr Late effects following isoniazid therapy.
title_full_unstemmed Late effects following isoniazid therapy.
title_short Late effects following isoniazid therapy.
title_sort late effects following isoniazid therapy.
topic Public Health, Environmental and Occupational Health
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description <jats:p> Amont 338 women treated in Massachusetts with isoniazid (isonicotinic acid hydrazide = INH) for pulmonary tuberculosis, no excess cancer deaths occurred (8 observed vs 8.3 expected) after 23 years (12.9 mean) of follow-up. There was an excess of cancer deaths (54 vs 35.7) among 1,090 patients who did not receive INH, partly due to radiogenic breast cancer resulting from multiple chest fluoroscopies to monitor pneumothorax. Increased deaths from liver cirrhosis (5 vs 0.8) were observed following INH use, suggesting that chronic as well as acute liver disease complicate this treatment. </jats:p>
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description <jats:p> Amont 338 women treated in Massachusetts with isoniazid (isonicotinic acid hydrazide = INH) for pulmonary tuberculosis, no excess cancer deaths occurred (8 observed vs 8.3 expected) after 23 years (12.9 mean) of follow-up. There was an excess of cancer deaths (54 vs 35.7) among 1,090 patients who did not receive INH, partly due to radiogenic breast cancer resulting from multiple chest fluoroscopies to monitor pneumothorax. Increased deaths from liver cirrhosis (5 vs 0.8) were observed following INH use, suggesting that chronic as well as acute liver disease complicate this treatment. </jats:p>
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spelling Boice, J D Fraumeni, J F 0090-0036 1541-0048 American Public Health Association Public Health, Environmental and Occupational Health http://dx.doi.org/10.2105/ajph.70.9.987 <jats:p> Amont 338 women treated in Massachusetts with isoniazid (isonicotinic acid hydrazide = INH) for pulmonary tuberculosis, no excess cancer deaths occurred (8 observed vs 8.3 expected) after 23 years (12.9 mean) of follow-up. There was an excess of cancer deaths (54 vs 35.7) among 1,090 patients who did not receive INH, partly due to radiogenic breast cancer resulting from multiple chest fluoroscopies to monitor pneumothorax. Increased deaths from liver cirrhosis (5 vs 0.8) were observed following INH use, suggesting that chronic as well as acute liver disease complicate this treatment. </jats:p> Late effects following isoniazid therapy. American Journal of Public Health
spellingShingle Boice, J D, Fraumeni, J F, American Journal of Public Health, Late effects following isoniazid therapy., Public Health, Environmental and Occupational Health
title Late effects following isoniazid therapy.
title_full Late effects following isoniazid therapy.
title_fullStr Late effects following isoniazid therapy.
title_full_unstemmed Late effects following isoniazid therapy.
title_short Late effects following isoniazid therapy.
title_sort late effects following isoniazid therapy.
title_unstemmed Late effects following isoniazid therapy.
topic Public Health, Environmental and Occupational Health
url http://dx.doi.org/10.2105/ajph.70.9.987