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Late effects following isoniazid therapy.
Gespeichert in:
Zeitschriftentitel: | American Journal of Public Health |
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Personen und Körperschaften: | , |
In: | American Journal of Public Health, 70, 1980, 9, S. 987-989 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
American Public Health Association
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Schlagwörter: |
author_facet |
Boice, J D Fraumeni, J F Boice, J D Fraumeni, J F |
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author |
Boice, J D Fraumeni, J F |
spellingShingle |
Boice, J D Fraumeni, J F American Journal of Public Health Late effects following isoniazid therapy. Public Health, Environmental and Occupational Health |
author_sort |
boice, j d |
spelling |
Boice, J D Fraumeni, J F 0090-0036 1541-0048 American Public Health Association Public Health, Environmental and Occupational Health http://dx.doi.org/10.2105/ajph.70.9.987 <jats:p> Amont 338 women treated in Massachusetts with isoniazid (isonicotinic acid hydrazide = INH) for pulmonary tuberculosis, no excess cancer deaths occurred (8 observed vs 8.3 expected) after 23 years (12.9 mean) of follow-up. There was an excess of cancer deaths (54 vs 35.7) among 1,090 patients who did not receive INH, partly due to radiogenic breast cancer resulting from multiple chest fluoroscopies to monitor pneumothorax. Increased deaths from liver cirrhosis (5 vs 0.8) were observed following INH use, suggesting that chronic as well as acute liver disease complicate this treatment. </jats:p> Late effects following isoniazid therapy. American Journal of Public Health |
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American Public Health Association, 1980 |
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American Public Health Association, 1980 |
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1980 |
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American Public Health Association |
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American Journal of Public Health |
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title |
Late effects following isoniazid therapy. |
title_unstemmed |
Late effects following isoniazid therapy. |
title_full |
Late effects following isoniazid therapy. |
title_fullStr |
Late effects following isoniazid therapy. |
title_full_unstemmed |
Late effects following isoniazid therapy. |
title_short |
Late effects following isoniazid therapy. |
title_sort |
late effects following isoniazid therapy. |
topic |
Public Health, Environmental and Occupational Health |
url |
http://dx.doi.org/10.2105/ajph.70.9.987 |
publishDate |
1980 |
physical |
987-989 |
description |
<jats:p> Amont 338 women treated in Massachusetts with isoniazid (isonicotinic acid hydrazide = INH) for pulmonary tuberculosis, no excess cancer deaths occurred (8 observed vs 8.3 expected) after 23 years (12.9 mean) of follow-up. There was an excess of cancer deaths (54 vs 35.7) among 1,090 patients who did not receive INH, partly due to radiogenic breast cancer resulting from multiple chest fluoroscopies to monitor pneumothorax. Increased deaths from liver cirrhosis (5 vs 0.8) were observed following INH use, suggesting that chronic as well as acute liver disease complicate this treatment. </jats:p> |
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author | Boice, J D, Fraumeni, J F |
author_facet | Boice, J D, Fraumeni, J F, Boice, J D, Fraumeni, J F |
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container_title | American Journal of Public Health |
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description | <jats:p> Amont 338 women treated in Massachusetts with isoniazid (isonicotinic acid hydrazide = INH) for pulmonary tuberculosis, no excess cancer deaths occurred (8 observed vs 8.3 expected) after 23 years (12.9 mean) of follow-up. There was an excess of cancer deaths (54 vs 35.7) among 1,090 patients who did not receive INH, partly due to radiogenic breast cancer resulting from multiple chest fluoroscopies to monitor pneumothorax. Increased deaths from liver cirrhosis (5 vs 0.8) were observed following INH use, suggesting that chronic as well as acute liver disease complicate this treatment. </jats:p> |
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spelling | Boice, J D Fraumeni, J F 0090-0036 1541-0048 American Public Health Association Public Health, Environmental and Occupational Health http://dx.doi.org/10.2105/ajph.70.9.987 <jats:p> Amont 338 women treated in Massachusetts with isoniazid (isonicotinic acid hydrazide = INH) for pulmonary tuberculosis, no excess cancer deaths occurred (8 observed vs 8.3 expected) after 23 years (12.9 mean) of follow-up. There was an excess of cancer deaths (54 vs 35.7) among 1,090 patients who did not receive INH, partly due to radiogenic breast cancer resulting from multiple chest fluoroscopies to monitor pneumothorax. Increased deaths from liver cirrhosis (5 vs 0.8) were observed following INH use, suggesting that chronic as well as acute liver disease complicate this treatment. </jats:p> Late effects following isoniazid therapy. American Journal of Public Health |
spellingShingle | Boice, J D, Fraumeni, J F, American Journal of Public Health, Late effects following isoniazid therapy., Public Health, Environmental and Occupational Health |
title | Late effects following isoniazid therapy. |
title_full | Late effects following isoniazid therapy. |
title_fullStr | Late effects following isoniazid therapy. |
title_full_unstemmed | Late effects following isoniazid therapy. |
title_short | Late effects following isoniazid therapy. |
title_sort | late effects following isoniazid therapy. |
title_unstemmed | Late effects following isoniazid therapy. |
topic | Public Health, Environmental and Occupational Health |
url | http://dx.doi.org/10.2105/ajph.70.9.987 |