Human-sized magnetic particle imaging for brain applications

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Veröffentlicht in:	Nature Communications Vol.10.2019, 1-9 Seiten, Article number 1936
Personen und Körperschaften:	Gräser, Matthias (VerfasserIn), Thieben, Florian (VerfasserIn), Szwargulski, Patryk (VerfasserIn), Werner, Franziska (VerfasserIn), Gdaniec, Nadine (VerfasserIn), Boberg, Marija (VerfasserIn), Griese, Florian (VerfasserIn), Möddel, Martin (VerfasserIn), Ludewig, Peter (VerfasserIn), Ven, Dionys van de (VerfasserIn), Weber, Oliver M. (VerfasserIn), Woywode, Oliver (VerfasserIn), Gleich, Bernhard (VerfasserIn), Knopp, Tobias (VerfasserIn), Technische Universität Hamburg (Sonstige), Institute for Biomedical Imaging (Sonstige)
Titel:	Human-sized magnetic particle imaging for brain applications/ M. Graeser, F. Thieben, P. Szwargulski, F. Werner, N. Gdaniec, M. Boberg, F. Griese, M. Möddel, P. Ludewig, D. van de Ven, O. M. Weber, O. Woywode, B. Gleich & T. Knopp
Format:	E-Book-Kapitel
Sprache:	Englisch
veröffentlicht:	2019
Gesamtaufnahme:	: Nature Communications, Vol.10.2019, 1-9 Seiten, Article number 1936 , volume:10
Quelle:	Verbunddaten SWB Lizenzfreie Online-Ressourcen

Details
Zusammenfassung:	Determining the brain perfusion is an important task for diagnosis of vascular diseases such as occlusions and intracerebral haemorrhage. Even after successful diagnosis, there is a high risk of restenosis or rebleeding such that patients need intense attention in the days after treatment. Within this work, we present a diagnostic tomographic imager that allows access to brain perfusion quantitatively in short intervals. The device is based on the magnetic particle imaging technology and is designed for human scale. It is highly sensitive and allows the detection of an iron concentration of 263 pmolFe ml-1, which is one of the lowest iron concentrations imaged by MPI so far. The imager is self-shielded and can be used in unshielded environments such as intensive care units. In combination with the low technical requirements this opens up a variety of medical applications and would allow monitoring of stroke on intensive care units.
Beschreibung:	Sonstige Körperschaft: Technische Universität Hamburg Sonstige Körperschaft: Technische Universität Hamburg, Institute for Biomedical Imaging
Umfang:	Illustrationen, Diagramme
ISSN:	2041-1723
DOI:	10.1038/s41467-019-09704-x