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The giant protein titin regulates the length of the striated muscle thick filament
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| Published in: | Nature Communications 8(2017) Artikel-Nummer 1041, 11 Seiten |
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| Authors and Corporations: | , |
| Title: | The giant protein titin regulates the length of the striated muscle thick filament/ Paola Tonino, Balazs Kiss, Josh Strom, Mei Methawasin, John E. Smith, Justin Kolb, Siegfried Labeit and Henk Granzier |
| Type of Resource: | E-Book Component Part |
| Language: | English |
| published: |
19 October 2017
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| Series: |
: Nature Communications, 8(2017) Artikel-Nummer 1041, 11 Seiten
, volume:8 |
| Source: | Verbunddaten SWB Lizenzfreie Online-Ressourcen |
| Abstract: | Thick filaments in skeletal muscle and heart are composed of myosin. The authors show that the length of thick filaments is defined by titin, and that alterations in titin length affect force generation and lead to dilated cardiomyopathy in mice. |
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| Item Description: | Gesehen am 28.08.2018 |
| Physical Description: | 11 |
| ISSN: |
2041-1723
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| DOI: | 10.1038/s41467-017-01144-9 |